2-Fluoro-3-methoxyphenylboronic acid
2-Fluoro-3-methoxyphenylboronic acid (CAS: 352303-67-4; Formula: C7H8BFO3; MW: 169.95) is a versatile aryl boronic acid derivative supplied by Tech Serve Solutions. It serves as a key reactant in regioselective Suzuki coupling reactions and is utilised in the preparation of specific inhibitors and boronic esters. This compound is essential for advanced organic synthesis within research and development settings.
Suzuki Coupling Reactions
This compound is a valuable reagent for regioselective Suzuki coupling, a cornerstone of modern cross-coupling chemistry for C-C bond formation.
Preparation of Enzyme Inhibitors
It is employed in the synthesis of inhibitors for 17β-hydroxysteroid dehydrogenase type 1, which are of interest in pharmaceutical research.
Boronic Ester Synthesis
The molecule can be readily converted into corresponding boronic esters, offering alternative reactivity and stability profiles for synthetic transformations.
| Molecular weight | 169.95 |
|---|---|
| Linear formula | FC6H3(OCH3)B(OH)2 |
| Application | Reactant for:• Regioselective Suzuki coupling1• Preparation of inhibitors of 17β-hydroxysteroid dehydrogenase type 12• Preparation of boronic esters3 |
| Melting point | 117-122 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-3-methoxyphenylboronic acid used for?
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2-Fluoro-3-methoxyphenylboronic acid is primarily used as a reactant in regioselective Suzuki coupling reactions, for the preparation of 17β-hydroxysteroid dehydrogenase type 1 inhibitors, and for the synthesis of boronic esters.
What are the CAS number and formula for 2-Fluoro-3-methoxyphenylboronic acid?
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The CAS number is 352303-67-4 and the chemical formula is C7H8BFO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-3-methoxyphenylboronic acid as a research or technical grade chemical. We do not represent it as meeting USP, BP, or EP pharmacopoeial standards.
How should 2-Fluoro-3-methoxyphenylboronic acid be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for full details.
Is 2-Fluoro-3-methoxyphenylboronic acid a controlled substance?
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The provided data does not indicate that 2-Fluoro-3-methoxyphenylboronic acid is a controlled substance.
How is this chemical packed and shipped?
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As a global supplier, Tech Serve Solutions ensures appropriate packaging for safe handling, storage, and export of chemicals, adhering to international regulations.
How can I request a quote or sample for 2-Fluoro-3-methoxyphenylboronic acid?
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Please contact our sales team via the website or your dedicated account manager to request a quote or a sample for 2-Fluoro-3-methoxyphenylboronic acid.
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