2-Ethylbutyryl chloride
2-Ethylbutyryl chloride (CAS 2736-40-5) is a clear liquid with the linear formula (C2H5)2CHC(O)Cl and a molecular weight of 134.60 g/mol. As an acid halide and organic building block, it serves as a versatile intermediate in chemical synthesis. Its reactivity makes it valuable for introducing the 2-ethylbutyryl group in various organic reactions, contributing to the development of diverse chemical compounds.

Organic Synthesis Intermediate
This compound functions as a key building block in organic synthesis. It is utilised to introduce the 2-ethylbutyryl moiety into target molecules, facilitating the creation of more complex chemical structures.
Acylation Reagent
As an acid chloride, 2-Ethylbutyryl chloride is a potent acylating agent. It readily reacts with nucleophiles such as alcohols and amines to form esters and amides, respectively, which are common functionalities in pharmaceuticals and fine chemicals.
Research and Development
It is employed in research laboratories for exploring novel synthetic pathways and developing new chemical entities. Its specific reactivity profile makes it suitable for specific transformations in academic and industrial R&D.
| Molecular weight | 134.60 |
|---|---|
| Linear formula | (C2H5)2CHC(O)Cl |
| Assay | 97% |
| Boiling point | 137-139 °C(lit.) |
| Density | 0.982 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.425(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 35 °C / 95 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Ethylbutyryl chloride primarily used for?
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2-Ethylbutyryl chloride is primarily used as an intermediate in organic synthesis and as an acylation reagent for introducing the 2-ethylbutyryl group into various chemical structures.
What are the CAS number and chemical formula for 2-Ethylbutyryl chloride?
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The CAS number for 2-Ethylbutyryl chloride is 2736-40-5, and its linear formula is (C2H5)2CHC(O)Cl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Ethylbutyryl chloride with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Ethylbutyryl chloride be handled safely?
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2-Ethylbutyryl chloride is a corrosive and flammable liquid. It is essential to handle it with appropriate personal protective equipment, including chemical-resistant gloves, safety goggles, face shield, and respiratory protection in a well-ventilated area. Avoid contact with skin, eyes, and clothing, and keep away from heat and open flames.
Is 2-Ethylbutyryl chloride a controlled substance?
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The provided data does not indicate that 2-Ethylbutyryl chloride is a controlled substance.
How is 2-Ethylbutyryl chloride packed, shipped, and exported?
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2-Ethylbutyryl chloride is packed in compliance with UN 2920 specifications for transport. Tech Serve Solutions offers global export services for this chemical.
How can I request a sample or quote for 2-Ethylbutyryl chloride?
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To request a sample or a quotation for 2-Ethylbutyryl chloride, please contact our sales team through the website or by phone.
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