2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (CAS: 163-57-59-8) is a heterocyclic organic compound with the molecular formula C14H17NO3 and a molecular weight of 247.29 g/mol. It serves as a valuable reagent in chemical synthesis, particularly noted for its application in peptide chemistry and coupling reactions. This compound functions as an irreversible antagonist for membrane-bound receptors, contributing to its utility in chemical biology research.
- IUPAC
- N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline,EEDQ,Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
- Synonyms
- N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinolineEEDQEthyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate

Chemical Biology Research
This compound acts as an irreversible antagonist for membrane-bound receptors. Its specific mechanism of action makes it a useful tool for studying receptor function and signaling pathways in biological systems.
Peptide Synthesis and Coupling
As a reagent in peptide chemistry, it facilitates coupling reactions. Its role in peptide synthesis aids in the efficient formation of peptide bonds, crucial for the construction of peptides and proteins.
Synthetic Reagent
This dihydroquinoline derivative is employed as a versatile synthetic reagent. It can be utilized in various organic transformations, contributing to the synthesis of complex organic molecules.
| Molecular weight | 247.29 |
|---|---|
| Empirical formula | C14H17NO3 |
| Assay | ≥99% |
| Storage temperature | 2-8°C |
| Application | Irreversible membrane-bound receptor antagonist.1,2 |
| Melting point | 62-67 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 38 |
| Safety statements (S) | 22-24/25 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline used for?
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2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (CAS: 16357-59-8) is primarily used as an irreversible membrane-bound receptor antagonist in chemical biology and as a reagent in peptide chemistry and coupling reactions for chemical synthesis.
What are the CAS number and formula for this compound?
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The CAS number is 16357-59-8, and its empirical formula is C14H17NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline with an assay of ≥99%. TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling this chemical?
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This compound is harmful if swallowed (H302) and causes skin irritation (H315). It is recommended to use a dust mask type N95 (US), eyeshields, and gloves. Store at 2-8°C.
How is this chemical packed and shipped?
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2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is packed and shipped according to international safety standards for chemical transport. Please contact us for specific export or bulk order details.
How can I request a sample or a quote?
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You can request a sample or a quote by contacting our sales team through the website or by calling us directly. Please reference the product name and CAS number (16357-59-8).
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