2′-Chloro-5′-(trifluoromethyl)acetophenone
2′-Chloro-5′-(trifluoromethyl)acetophenone (CAS: 71648-45-8) is a trifluoromethylated aromatic ketone. With the molecular formula ClC<sub>6</sub>H<sub>3</sub>(CF<sub>3</sub>)COCH<sub>3</sub> and a molecular weight of 222.59 g/mol, this compound serves as a valuable building block in organic synthesis. It is frequently employed in the preparation of more complex molecules, particularly within the pharmaceutical and agrochemical industries, due to the presence of the reactive ketone and the electron-withdrawing trifluoromethyl group.
- IUPAC
- 2-Chloro-5-(trifluoromethyl)acetophenone
Pharmaceutical Intermediate
This compound is utilised as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its structure allows for diverse chemical modifications to build complex drug molecules.
Agrochemical Synthesis
It serves as a precursor in the development of novel pesticides and herbicides, contributing to the creation of effective crop protection agents.
Organic Building Block
The compound is a versatile building block in general organic synthesis, enabling researchers to introduce specific functional groups into target molecules.
Research and Development
Used in academic and industrial R&D settings for exploring new synthetic routes and developing innovative chemical entities.
| Molecular weight | 222.59 |
|---|---|
| Linear formula | ClC6H3(CF3)COCH3 |
| Assay | 97% |
| Boiling point | 204-205 °C(lit.) |
| Density | 1.392 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4810(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 91 °C / 195.8 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Chloro-5′-(trifluoromethyl)acetophenone used for?
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2′-Chloro-5′-(trifluoromethyl)acetophenone is primarily used as a building block in organic synthesis, particularly for the preparation of pharmaceutical intermediates and agrochemicals.
What is the CAS number and chemical formula for this compound?
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The CAS number is 71648-45-8 and the linear formula is ClC<sub>6</sub>H<sub>3</sub>(CF<sub>3</sub>)COCH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 2′-Chloro-5′-(trifluoromethyl)acetophenone be handled and stored?
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Handle with appropriate personal protective equipment, including eyeshields, gloves, and a respirator, in a well-ventilated area. Store in a cool, dry place away from incompatible materials. Refer to the Safety Data Sheet for detailed handling and safety information.
Is 2′-Chloro-5′-(trifluoromethyl)acetophenone shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2′-Chloro-5′-(trifluoromethyl)acetophenone, and can arrange international shipments.
How can I request a sample or quote for 2′-Chloro-5′-(trifluoromethyl)acetophenone?
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To request a sample or quote, please contact our sales department through the website or via direct inquiry, providing your specific requirements.
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