2-Chloro-4-pyridinylboronic acid
2-Chloro-4-pyridinylboronic acid (CAS: 458532-96-2), with the molecular formula Cl(C5H3N)B(OH)2 and a molecular weight of 157.36 g/mol, is a valuable organometallic reagent. This compound serves as a key substrate in peroxide-mediated hydroxydeboronation reactions, enabling the efficient synthesis of halohydroxypyridines. It is frequently employed in chemical synthesis and research laboratories.
- IUPAC
- 2-Chloropyridine-4-boronic acid
- Synonyms
- 2-Chloropyridine-4-boronic acid
Hydroxydeboronation Reactions
2-Chloro-4-pyridinylboronic acid is a substrate in peroxide-mediated hydroxydeboronation reactions. This process yields halohydroxypyridines with good efficiency.
Chemical Synthesis Intermediate
Utilised as a building block in complex organic synthesis pathways. Its specific structure allows for targeted functionalisation in the preparation of advanced intermediates and target molecules.
Heteroaryl Boronic Acid Applications
As a heteroaryl boronic acid derivative, it finds application in cross-coupling reactions and the synthesis of novel heterocyclic compounds relevant to pharmaceutical and materials science research.
| Molecular weight | 157.36 |
|---|---|
| Linear formula | Cl(C5H3N)B(OH)2 |
| Assay | ≥95.0% |
| Storage temperature | 2-8°C |
| Application | Substrate in a peroxide mediated hydroxydeboronation providing good yields of halohydroxypyridines.1 |
| Melting point | 155-163 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-pyridinylboronic acid used for?
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2-Chloro-4-pyridinylboronic acid is used as a substrate in peroxide-mediated hydroxydeboronation reactions for synthesising halohydroxypyridines, and as an intermediate in chemical synthesis and research.
What is the CAS number and chemical formula for 2-Chloro-4-pyridinylboronic acid?
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The CAS number is 458532-96-2 and the chemical formula is Cl(C5H3N)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-pyridinylboronic acid with a purity of ≥95.0%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound is a Warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
How is 2-Chloro-4-pyridinylboronic acid shipped and exported?
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As a specialist global supplier, Tech Serve Solutions exports 2-Chloro-4-pyridinylboronic acid worldwide. It is typically stored at 2-8°C.
How can I request a sample or a quote for 2-Chloro-4-pyridinylboronic acid?
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To request a sample or a quote, please contact our sales team through the website or by telephone, providing the product name and CAS number.
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