2-Chloro-4-methylaniline
2-Chloro-4-methylaniline (CAS 615-65-6), a chlorinated derivative of p-toluidine with the molecular formula ClC₆H₃(CH₃)NH₂, is a valuable organic intermediate. Possessing a molecular weight of 141.60 g/mol, it is primarily utilised in chemical synthesis, particularly as a building block in the creation of more complex molecules. Its applications extend to analytical chemistry for the determination of aniline and amine derivatives in environmental samples.
- IUPAC
- 2-Chloro-p-toluidine,4-Amino-3-chlorotoluene
- Synonyms
- 2-Chloro-p-toluidine4-Amino-3-chlorotoluene
Environmental Analysis
2-Chloro-4-methylaniline has been employed in analytical methodologies for the detection of aniline derivatives in environmental water samples, often in conjunction with techniques like liquid chromatography.
Organic Synthesis Intermediate
As a substituted aniline, this compound serves as a key building block in organic synthesis, enabling the construction of diverse chemical structures for research and development purposes.
Amine Determination
It has also been utilised in methods for determining the presence of amines in environmental water samples using gas chromatography-mass spectrometry.
| Molecular weight | 141.60 |
|---|---|
| Linear formula | ClC6H3(CH3)NH2 |
| Assay | 98% |
| Boiling point | 223-225 °C(lit.) |
| Density | 1.151 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.575(lit.) |
| Solubility | methanol: soluble |
| Melting point | 7 °C(lit.) |
| Application | 2-Chloro-4-methylaniline was used in determination of aniline derivatives in environmental water samples using on-line combination of supported liquid membrane extraction and liquid chromatography1. It was also used in determination of amines in environmental water samples by gas chromatography–mass spectrometry2. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 99 °C / 210.2 °F |
| Transport (UN / ADR) | UN 3429 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-methylaniline used for?
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2-Chloro-4-methylaniline is used as a building block in chemical synthesis and in analytical chemistry for the determination of aniline and amine derivatives in environmental water samples.
What are the CAS number and molecular formula for 2-Chloro-4-methylaniline?
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The CAS number is 615-65-6 and the molecular formula is ClC₆H₃(CH₃)NH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-methylaniline with an assay of 98%. This is a technical/research grade, and we do not represent it as USP, BP, or EP grade.
How should 2-Chloro-4-methylaniline be handled safely?
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2-Chloro-4-methylaniline is classified as dangerous. It is harmful if swallowed, in contact with skin, or if inhaled, causes skin irritation, and causes serious eye damage. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, and ensure good ventilation.
Is 2-Chloro-4-methylaniline a controlled substance?
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The provided data does not indicate that 2-Chloro-4-methylaniline is a controlled substance.
How is 2-Chloro-4-methylaniline packed, shipped, or exported?
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2-Chloro-4-methylaniline is packaged and shipped in accordance with international regulations for hazardous materials, identified under UN 3429, Class 6.1, Packing Group III.
How can I request a sample or quote for 2-Chloro-4-methylaniline?
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Please contact our sales department through the website or by phone to request a sample or a quotation for 2-Chloro-4-methylaniline.
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