2-Butoxy-5-fluorophenylboronic acid
2-Butoxy-5-fluorophenylboronic acid (CAS: 480438-62-8, Formula: C10H14BFO3, MW: 212.03) is a disubstituted aryl boronic acid. This organoboron compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. It is essential for constructing complex molecules within the pharmaceutical and fine chemical industries, offering a key intermediate for developing novel compounds and advanced materials.

Suzuki-Miyaura Cross-Coupling Reactions
2-Butoxy-5-fluorophenylboronic acid is widely utilised as a coupling partner in Suzuki-Miyaura reactions. This enables the formation of new carbon-carbon bonds, facilitating the synthesis of biaryl compounds and other complex organic structures.
Pharmaceutical Intermediate Synthesis
The compound acts as a crucial intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its specific structural features allow for the introduction of desired aryl moieties into drug candidates.
Material Science
This boronic acid derivative can be employed in the development of advanced materials. Its incorporation into organic frameworks may influence electronic or optical properties.
Agrochemical Research
It finds application in the research and development of new agrochemicals, where its unique structure can contribute to the design of novel pesticides or herbicides.
| Molecular weight | 212.03 |
|---|---|
| Empirical formula | C10H14BFO3 |
| Melting point | 61-66 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Butoxy-5-fluorophenylboronic acid used for?
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2-Butoxy-5-fluorophenylboronic acid is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, and as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and formula for 2-Butoxy-5-fluorophenylboronic acid?
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The CAS number for 2-Butoxy-5-fluorophenylboronic acid is 480438-62-8, and its empirical formula is C10H14BFO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a research-grade reagent. The specific assay will be detailed on the Certificate of Analysis provided with your order. We do not represent this product as USP, BP, or EP grade.
How should 2-Butoxy-5-fluorophenylboronic acid be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet (SDS) for comprehensive safety information.
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that 2-Butoxy-5-fluorophenylboronic acid is a controlled substance.
How is 2-Butoxy-5-fluorophenylboronic acid packed and shipped?
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Products are carefully packed and exported in compliance with international shipping regulations for chemical compounds. Specific packaging details are available upon request.
How can I request a quote or sample?
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To request a quote or a sample of 2-Butoxy-5-fluorophenylboronic acid, please contact our sales team through the TSS website or via direct inquiry, providing your specific requirements.
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