2-Butoxy-4-fluorophenylboronic acid
2-Butoxy-4-fluorophenylboronic acid (CAS: 480438-61-7) is a disubstituted aryl boronic acid with the molecular formula H₃C(CH₂)₃OC₆H₃(F)B(OH)₂ and a molecular weight of 212.03 g/mol. This organoboronic acid derivative is valuable in organic synthesis, particularly in cross-coupling reactions such as the Suzuki-Miyaura coupling, enabling the formation of carbon-carbon bonds. It serves as a key building block for complex organic molecules in research and development.
Suzuki-Miyaura Cross-Coupling Reactions
This boronic acid is an excellent substrate for palladium-catalyzed Suzuki-Miyaura cross-coupling reactions. It facilitates the formation of C-C bonds by reacting with aryl or vinyl halides, enabling the synthesis of biaryl compounds and substituted alkenes.
Organic Synthesis Building Block
As a functionalised aryl boronic acid, it serves as a versatile building block in the construction of complex organic molecules. Its specific substitution pattern allows for targeted derivatisation in multi-step synthetic pathways.
Pharmaceutical Intermediate Synthesis
The structural features of 2-butoxy-4-fluorophenylboronic acid make it a useful intermediate in the synthesis of potential pharmaceutical agents and active pharmaceutical ingredients (APIs). Its incorporation can introduce specific aryl moieties into drug candidates.
Materials Science Research
Organoboronic acids are increasingly explored in materials science for the development of novel organic electronic materials. This compound could be employed in the synthesis of conjugated polymers or other advanced materials.
| Molecular weight | 212.03 |
|---|---|
| Linear formula | H3C(CH2)3OC6H3(F)B(OH)2 |
| Melting point | 88-93 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Butoxy-4-fluorophenylboronic acid used for?
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2-Butoxy-4-fluorophenylboronic acid is primarily used as a building block in organic synthesis, notably in Suzuki-Miyaura cross-coupling reactions for forming carbon-carbon bonds, and in the development of pharmaceutical intermediates and advanced materials.
What is the CAS number and molecular formula?
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The CAS number for 2-Butoxy-4-fluorophenylboronic acid is 480438-61-7, and its molecular formula is H₃C(CH₂)₃OC₆H₃(F)B(OH)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound typically as a research or technical grade chemical. We do not represent it as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
What are the safety and handling precautions?
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Handle with care, wearing appropriate personal protective equipment including eyeshields and gloves. Use in a well-ventilated area or with respiratory protection (type N95 respirator filter or type P1 filter to EN143).
Is this compound a controlled substance?
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Based on the provided data, there is no indication that 2-Butoxy-4-fluorophenylboronic acid is a controlled substance.
How is this chemical packed and shipped?
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Tech Serve Solutions professionally packs and exports chemicals globally, adhering to all relevant shipping regulations for hazardous materials.
How can I request a quote or sample?
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Please use the contact form on our website or contact our sales department directly to request a quotation or a sample.
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