2-Bromobenzyl bromide
2-Bromobenzyl bromide (CAS: 3433-80-5), with the chemical formula BrC<sub>6</sub>H<sub>4</sub>CH<sub>2</sub>Br, is a halogenated aromatic compound. Its molecular weight is 249.93 g/mol. This dibrominated toluene derivative serves as a valuable building block in organic synthesis, particularly for introducing the 2-bromobenzyl moiety into various molecular structures. It is primarily used in research and chemical synthesis.
- IUPAC
- α,2-Dibromotoluene
- Synonyms
- α,2-Dibromotoluene
Synthesis of Substituted Quinolines
2-Bromobenzyl bromide has been employed in the synthesis of substituted quinazolines and 1,2,3,4-tetrahydroquinazolines, demonstrating its utility in the construction of heterocyclic frameworks.
Preparation of Indene Derivatives
This compound serves as a precursor for the synthesis of 2- and 3-substituted indenes, expanding its application in the creation of complex organic molecules.
Formation of Tribenzylamine Structures
It is used in the preparation of molecules such as <i>tris</i>-2-bromotribenzylamine, highlighting its role in building elaborate organic structures.
| Molecular weight | 249.93 |
|---|---|
| Linear formula | BrC6H4CH2Br |
| Assay | ≥97.0% (GC) |
| Boiling point | 129 °C/19 mmHg(lit.) |
| Refractive index | n20/D 1.619(lit.) |
| Solubility | dioxane: soluble1 g/10 mL, clear, colorless to almost colorless |
| Application | 2-Bromobenzyl bromide was used in the synthesis of:• substituted quinazolines and 1,2,3,4-tetrahydroquinazolines1• 2- and 3-substituted indenes2• tris-2-bromotribenzylamine3 |
| Melting point | 29-32 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromobenzyl bromide used for?
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2-Bromobenzyl bromide is used as a building block in organic synthesis, including the preparation of substituted quinazolines, tetrahydroquinazolines, indene derivatives, and tris-2-bromotribenzylamine.
What are the CAS number and chemical formula for 2-Bromobenzyl bromide?
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The CAS number for 2-Bromobenzyl bromide is 3433-80-5, and its chemical formula is BrC<sub>6</sub>H<sub>4</sub>CH<sub>2</sub>Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromobenzyl bromide with a purity of ≥97.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Bromobenzyl bromide be handled safely?
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2-Bromobenzyl bromide is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires appropriate personal protective equipment, including eyeshields, faceshields, suitable gloves, and respiratory protection. Always consult the Safety Data Sheet before use.
Is 2-Bromobenzyl bromide suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Bromobenzyl bromide.
How can I request a sample or quote for 2-Bromobenzyl bromide?
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To request a sample or quote for 2-Bromobenzyl bromide, please contact our sales team through the website or by phone.
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