2′-Bromoacetophenone
2′-Bromoacetophenone (CAS 2142-69-0) is an organic compound with the molecular formula C<sub>8</sub>H<sub>7</sub>BrO and a molecular weight of 199.04 g/mol. This bromo-ketone serves as a versatile intermediate in organic synthesis, particularly in the preparation of various heterocyclic compounds and complex organic molecules. Its reactivity makes it a valuable building block for researchers and manufacturers in the chemical and pharmaceutical industries.
- IUPAC
- 1-Acetyl-2-bromobenzene
- Synonyms
- 1-Acetyl-2-bromobenzene2-Bromoacetophenone

Organic Synthesis Intermediate
2′-Bromoacetophenone is widely employed as a key intermediate in the synthesis of diverse organic compounds. It is particularly useful for introducing the acetophenone moiety into larger molecular structures.
Heterocyclic Chemistry
This compound has been utilized in the construction of novel heterocyclic systems. For example, it was used in the synthesis of unique non-condensed 5,5-bicyclic structures, showcasing its utility in complex ring formations.
Research and Development
As a readily available building block, 2′-Bromoacetophenone is frequently used in academic and industrial research laboratories for exploring new synthetic routes and developing novel chemical entities.
| Molecular weight | 199.04 |
|---|---|
| Linear formula | BrC6H4COCH3 |
| Assay | 99% |
| Density | 1.476 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.568(lit.) |
| Application | 2′-Bromoacetophenone (2-Bromoacetophenone) was used in the synthesis of novel series of non-condensed 5,5-bicycles1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Bromoacetophenone used for?
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2′-Bromoacetophenone is primarily used as an intermediate in organic synthesis, particularly for creating heterocyclic compounds and as a building block in chemical research and development.
What are the CAS number and formula for 2′-Bromoacetophenone?
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The CAS number for 2′-Bromoacetophenone is 2142-69-0, and its linear formula is BrC<sub>6</sub>H<sub>4</sub>COCH<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Bromoacetophenone with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 2′-Bromoacetophenone be handled safely?
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2′-Bromoacetophenone is a warning compound that causes skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (e.g., type ABEK respirator filter), must be used.
Is 2′-Bromoacetophenone a controlled substance?
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The provided data does not indicate that 2′-Bromoacetophenone is a controlled substance.
How is 2′-Bromoacetophenone packed and exported by TSS?
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Tech Serve Solutions expertly handles the packing and global export of 2′-Bromoacetophenone, ensuring compliance with international shipping regulations.
How can I request a sample or quote for 2′-Bromoacetophenone?
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To request a sample or a quote for 2′-Bromoacetophenone, please contact our sales team via the website or direct inquiry.
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