2-Bromo-6-nitrotoluene
2-Bromo-6-nitrotoluene (CAS: 55289-35-5), with the molecular formula CH3C6H3(NO2)Br and a molecular weight of 216.03 g/mol, is a valuable organic building block. This compound, assaying at 97%, serves as a key intermediate in complex chemical syntheses, including the preparation of biologically active molecules. Its utility is demonstrated in research involving the total synthesis of clavicipitic acid derivatives and carbazole alkaloids.
Synthesis of Clavicipitic Acid Derivatives
2-Bromo-6-nitrotoluene is utilised as a starting reagent in the total synthesis of N-acetyl methyl ester of (±)-clavicipitic acids. This application highlights its role in creating complex natural product analogues.
Preparation of Carbazomadurin A
The compound has been employed in the synthesis of carbazomadurin A, a highly oxygenated alkaloid known for its neuronal cell protecting properties. This showcases its importance in medicinal chemistry research.
Organic Synthesis Intermediate
As a nitro compound and organic building block, 2-Bromo-6-nitrotoluene is a versatile intermediate for constructing more complex organic molecules. It facilitates the introduction of specific functional groups in multi-step synthetic pathways.
| Molecular weight | 216.03 |
|---|---|
| Linear formula | CH3C6H3(NO2)Br |
| Assay | 97% |
| Boiling point | 143 °C/22 mmHg(lit.) |
| Application | 2-Bromo-6-nitrotoluene has been used:• as starting reagent in total synthesis of N-acetyl methyl ester of (±)-clavicipitic acids1• in synthesis of carbazomadurin A, highly oxygenated neuronal cell protecting carbazole alkaloid2 |
| Melting point | 38-40 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-6-nitrotoluene used for?
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2-Bromo-6-nitrotoluene is used as a starting reagent in the total synthesis of N-acetyl methyl ester of (±)-clavicipitic acids and in the synthesis of carbazomadurin A, a neuronal cell protecting carbazole alkaloid. It serves as a versatile intermediate in organic synthesis.
What are the CAS number and chemical formula for 2-Bromo-6-nitrotoluene?
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The CAS number for 2-Bromo-6-nitrotoluene is 55289-35-5, and its chemical formula is CH3C6H3(NO2)Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-6-nitrotoluene with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling precautions for 2-Bromo-6-nitrotoluene?
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2-Bromo-6-nitrotoluene is a Warning substance with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is 2-Bromo-6-nitrotoluene packed, shipped, and exported?
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Tech Serve Solutions carefully packs and ships chemicals according to international regulations, ensuring safe transit for export. Specific packaging details are available upon request for your order.
How can I request a sample or quote for 2-Bromo-6-nitrotoluene?
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To request a sample or a quote for 2-Bromo-6-nitrotoluene, please contact our sales team through the website or by phone. Provide your specific requirements and shipping details.
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