2-Bromo-5-(trifluoromethyl)aniline
2-Bromo-5-(trifluoromethyl)aniline (CAS: 454-79-5) is a halogenated aromatic amine with the molecular formula BrC6H3(CF3)NH2 and a molecular weight of 240.02 g/mol. This compound serves as a valuable intermediate in organic synthesis. Its structure, featuring both bromine and trifluoromethyl substituents on an aniline core, makes it useful in the development of novel pharmaceutical agents and other fine chemicals. TSS supplies this reagent for research and industrial applications.
Hepatitis C Virus (HCV) NS3 Protease Inhibitor Synthesis
2-Bromo-5-(trifluoromethyl)aniline has been utilised in the preparation and evaluation of chemical compounds designed to inhibit the NS3 protease of the Hepatitis C virus. This application highlights its role in antiviral drug discovery research.
Organic Building Block
As a versatile organic building block, this compound is employed in the synthesis of more complex molecules. Its reactive functional groups allow for diverse chemical transformations in academic and industrial research settings.
Pharmaceutical Intermediate
The compound serves as a key intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its specific structural features are leveraged to construct targeted drug candidates.
| Molecular weight | 240.02 |
|---|---|
| Linear formula | BrC6H3(CF3)NH2 |
| Assay | 97% |
| Density | 1.675 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.522(lit.) |
| Application | 2-Bromo-5-(trifluoromethyl)aniline was used in the synthesis and biochemical evaluation of series of inhibitors of hepatitis C virus (HCV) NS3 protease1. |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3267 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-5-(trifluoromethyl)aniline used for?
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2-Bromo-5-(trifluoromethyl)aniline is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceutical agents such as inhibitors of the Hepatitis C virus (HCV) NS3 protease.
What is the CAS number and chemical formula for 2-Bromo-5-(trifluoromethyl)aniline?
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The CAS number is 454-79-5, and its chemical formula is BrC6H3(CF3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-5-(trifluoromethyl)aniline with a minimum assay of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Bromo-5-(trifluoromethyl)aniline be handled safely?
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2-Bromo-5-(trifluoromethyl)aniline is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Safe handling requires appropriate personal protective equipment, including full-face respirators, gloves, and eye protection. Always consult the Safety Data Sheet (SDS) before use.
Is 2-Bromo-5-(trifluoromethyl)aniline available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals. 2-Bromo-5-(trifluoromethyl)aniline is available for international shipment.
How can I request a sample or quote for 2-Bromo-5-(trifluoromethyl)aniline?
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To request a sample or obtain a quote, please visit the Tech Serve Solutions website or contact our sales team directly. Please reference the product name and CAS number (454-79-5).
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