2-Bromo-4-methoxyphenylacetic acid
2-Bromo-4-methoxyphenylacetic acid (CAS: 66916-99-2; Formula: H3COC6H3(Br)CH2CO2H; Molar Mass: 245.07 g/mol) is a valuable organic building block. This carboxylic acid derivative, featuring both a bromine atom and a methoxy group on the phenyl ring, serves as a versatile intermediate in complex organic synthesis and research chemical applications. Its specific structure allows for diverse chemical transformations, making it useful in the development of new molecules.

Organic Synthesis Intermediate
Utilised as a key building block in the synthesis of more complex organic molecules. Its functional groups, the carboxylic acid and the aryl bromide, allow for various coupling and derivatisation reactions.
Pharmaceutical Research
A useful compound in medicinal chemistry research for the preparation of potential drug candidates. The phenylacetic acid core is present in several classes of biologically active compounds.
Material Science
Can be employed in the development of novel materials where its specific structural features can be incorporated into polymer backbones or functionalised surfaces.
Academic Research
A reagent for academic laboratories exploring new synthetic methodologies or investigating structure-activity relationships in novel chemical entities.
| Molecular weight | 245.07 |
|---|---|
| Linear formula | H3COC6H3(Br)CH2CO2H |
| Assay | 97% |
| Melting point | 127-131 °C(lit.) |


Hazard statements
- H301Toxic if swallowed
- H319Causes serious eye irritation
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1/PG 3 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-50 |
| Safety statements (S) | 60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-4-methoxyphenylacetic acid used for?
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2-Bromo-4-methoxyphenylacetic acid (CAS: 66916-99-2) is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and the development of new molecules. Its functional groups enable diverse chemical transformations.
What are the CAS number and formula for 2-Bromo-4-methoxyphenylacetic acid?
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The CAS number is 66916-99-2, and the molecular formula is H3COC6H3(Br)CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-4-methoxyphenylacetic acid with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Bromo-4-methoxyphenylacetic acid be handled safely?
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This compound is toxic if swallowed and causes serious eye irritation. It is also very toxic to aquatic life with long lasting effects. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, faceshields, and gloves. Ensure adequate ventilation and avoid release into the environment.
Is 2-Bromo-4-methoxyphenylacetic acid a controlled substance?
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The provided data does not indicate that 2-Bromo-4-methoxyphenylacetic acid is a controlled substance.
How is 2-Bromo-4-methoxyphenylacetic acid packed and shipped?
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2-Bromo-4-methoxyphenylacetic acid is shipped according to UN 2811 regulations for toxic solids, organic, n.o.s. (6.1/PG 3). TSS exports this chemical globally, adhering to all relevant shipping and handling requirements.
How can I request a sample or quote for 2-Bromo-4-methoxyphenylacetic acid?
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To request a sample or obtain a quote for 2-Bromo-4-methoxyphenylacetic acid, please contact our sales department through the TSS website or by phone.
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