2-Amino-4-methylbenzophenone
2-Amino-4-methylbenzophenone (CAS: 4937-62-6) is an organic compound with the formula H2NC6H3(CH3)C(O)C6H5 and a molecular weight of 211.26 g/mol. This chemical serves as a valuable building block in organic synthesis, particularly in the creation of complex heterocyclic structures. Its utility is demonstrated in research and development, contributing to the synthesis of novel quinoline and benzodiazepine derivatives. Available from Tech Serve Solutions with an assay of 99%.
Synthesis of Quinolines
2-Amino-4-methylbenzophenone is a key starting material for the synthesis of substituted quinolines, such as 4-phenyl-7-methyl-2-(2′-pyridyl)quinoline and its methylated analogue.
Benzodiazepine Intermediate
This compound has been employed in the preparation of complex benzodiazepine structures, including N-tert-butyl-2-{3(R)-[3-(3-chlorophenyl)ureido]-8-methyl-2-oxo-5(R)-phenyl-1,3,4,5-tetrahydrobenz[b]azepin-1-yl}acetamide.
Organic Building Block
As a versatile organic building block, it facilitates the introduction of both amino and benzophenone functionalities into target molecules for further chemical elaboration.
| Molecular weight | 211.26 |
|---|---|
| Linear formula | H2NC6H3(CH3)C(O)C6H5 |
| Assay | 99% |
| Application | 2-Amino-4-methylbenzophenone has been used as starting reagent in the synthesis of: • 4-phenyl-7-methyl-2-(2′-pyridyl)quinoline and 4-phenyl-7-methyl-2-[2′-(6′-methyl)pyridyl]-quinoline1• N-tert-butyl-2-{3(R)-[3-(3-chlorophenyl)ureido]-8-methyl-2-oxo-5(R)-phenyl-1,3,4,5-tetrahydrobenz[b]azepin-1-yl}acetamide2 |
| Melting point | 65-66 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4-methylbenzophenone used for?
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2-Amino-4-methylbenzophenone is primarily used as a building block in organic synthesis, specifically in the preparation of quinoline and benzodiazepine derivatives.
What are the CAS number and chemical formula for 2-Amino-4-methylbenzophenone?
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The CAS number is 4937-62-6 and the chemical formula is H2NC6H3(CH3)C(O)C6H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-4-methylbenzophenone with a purity of 99%. This is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.
How should 2-Amino-4-methylbenzophenone be handled safely?
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2-Amino-4-methylbenzophenone is classified as a Warning. It can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Use a dust mask type N95, wear eyeshields and gloves. Ensure good ventilation.
Is 2-Amino-4-methylbenzophenone a controlled substance?
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The provided data does not indicate that 2-Amino-4-methylbenzophenone is a controlled substance.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging details for 2-Amino-4-methylbenzophenone depend on order size and destination, adhering to all relevant shipping regulations.
How can I request a sample or quote for 2-Amino-4-methylbenzophenone?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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