2-Amino-3,5-difluoro-4-(trifluoromethyl)pyridine
2-Amino-3,5-difluoro-4-(trifluoromethyl)pyridine (CAS 883498-68-8) is a fluorinated heterocyclic building block with the molecular formula C6H3F5N2 and a molecular weight of 198.09 g/mol. This compound is a valuable intermediate in organic synthesis, particularly for the development of novel fluorinated compounds. Its unique structure makes it suitable for applications in medicinal chemistry and materials science, offering a reactive amine group and a highly fluorinated pyridine core for further functionalization.
- Synonyms
- C6H3F5N2
Organic Synthesis Intermediate
This compound serves as a versatile building block in the synthesis of complex organic molecules. Its difluorinated and trifluoromethylated pyridine structure allows for the introduction of specific fluorinated motifs into target compounds.
Medicinal Chemistry
As a fluorinated heterocyclic, it is employed in the design and synthesis of new pharmaceutical candidates. Fluorine atoms can influence lipophilicity, metabolic stability, and binding affinity of drug molecules.
Materials Science
The unique electronic properties conferred by fluorine atoms make this pyridine derivative of interest in the development of advanced materials, such as functional polymers or electronic components.
| Molecular weight | 198.09 |
|---|---|
| Empirical formula | C6H3F5N2 |
| Assay | 95% |
| Density | 1.524 g/mL at 25 °C |
| Refractive index | n20/D 1.463 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-3,5-difluoro-4-(trifluoromethyl)pyridine used for?
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2-Amino-3,5-difluoro-4-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly for creating fluorinated compounds relevant to medicinal chemistry and materials science.
What is the CAS number and molecular formula?
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The CAS number is 883498-68-8 and the molecular formula is C6H3F5N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a minimum assay of 95%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling precautions for this chemical?
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This compound is classified as a Warning (GHS07) and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields and suitable gloves and respirator, must be used. Ensure good ventilation. Refer to the Safety Data Sheet (SDS) for detailed handling information.
How are chemicals like this packed, shipped, and exported?
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Tech Serve Solutions packages chemicals according to international shipping regulations (e.g., NA 1993, PGIII). We are experienced in exporting fine chemicals globally, ensuring compliance and product integrity.
How can I request a sample or quote for this product?
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Please contact our sales team directly through our website or by phone to request a sample or a quotation for 2-Amino-3,5-difluoro-4-(trifluoromethyl)pyridine.
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