2-Amino-1,3,4-thiadiazole
2-Amino-1,3,4-thiadiazole (CAS: 4005-51-0) is a versatile heterocyclic compound with the molecular formula C2H3N3S and a molecular weight of 101.13 g/mol. This white to off-white crystalline solid serves as a valuable building block in organic synthesis. Its structure, featuring a thiadiazole ring with an amino substituent, makes it an important intermediate for the development of diverse chemical entities, particularly in pharmaceutical research and material science.
- IUPAC
- 1,3,4-Thiadiazol-2-amine
- Synonyms
- 4005-51-0C2H3N3S1,3,4-Thiadiazol-2-amine

Pharmaceutical Intermediate
2-Amino-1,3,4-thiadiazole is a key intermediate in the synthesis of various pharmaceutical agents. Its heterocyclic scaffold is incorporated into molecules designed for potential therapeutic applications, including antimicrobial and anticancer research.
Agrochemical Synthesis
The compound finds application in the development of agrochemicals. Its unique structure can be modified to create novel pesticides, herbicides, or fungicides, contributing to crop protection.
Material Science
This thiadiazole derivative can be utilised in material science for the synthesis of functional materials. Its incorporation into polymers or other advanced materials may impart specific electronic or optical properties.
Organic Synthesis Reagent
As a readily available building block, 2-Amino-1,3,4-thiadiazole is employed in general organic synthesis for creating more complex molecular structures and exploring novel chemical transformations.
| Molecular weight | 101.13 |
|---|---|
| Empirical formula | C2H3N3S |
| Assay | 97% |
| Solubility | water: soluble25 mg/mL, clear, colorless |
| Melting point | 188-191 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-1,3,4-thiadiazole used for?
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2-Amino-1,3,4-thiadiazole is primarily used as a building block and intermediate in organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and functional materials.
What are the CAS number and formula for 2-Amino-1,3,4-thiadiazole?
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The CAS number for 2-Amino-1,3,4-thiadiazole is 4005-51-0, and its empirical formula is C2H3N3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-1,3,4-thiadiazole with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Amino-1,3,4-thiadiazole be handled safely?
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Handle 2-Amino-1,3,4-thiadiazole with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid inhalation of dust and ensure adequate ventilation. It is classified as harmful if swallowed and causes skin and eye irritation.
Is 2-Amino-1,3,4-thiadiazole available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Amino-1,3,4-thiadiazole, catering to international research and industrial needs.
How can I request a sample or quote for 2-Amino-1,3,4-thiadiazole?
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To request a sample or a quotation, please contact our sales department through the website or by direct inquiry, providing your specific requirements.
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