2,6-Dichlorobenzoyl chloride
2,6-Dichlorobenzoyl chloride (CAS: 4659-45-4), with the linear formula Cl₂C₆H₃COCl and a molecular weight of 209.46 g/mol, is a reactive acid halide. It serves as a key building block in organic synthesis, particularly in the development of novel protease inhibitors and the creation of complex organic molecules. Its applications span various fields requiring precise chemical modification.
- Synonyms
- 2,6-Dichlorobenzoyl chlorideCl2C6H3COCl
Protease Inhibitor Development
Utilised in substrate activity screening for the discovery of novel substrates and their subsequent conversion into non-peptidic inhibitors of cysteine and serine proteases.
Organic Synthesis Intermediate
Employed in the synthesis of specific organic compounds, such as 1-acyliridoles, contributing to the construction of diverse molecular architectures.
Enantiocontrolled Synthesis
Applied in enantiocontrolled total synthesis strategies, as demonstrated in the preparation of (-)-aspicilin, a complex natural product.
| Molecular weight | 209.46 |
|---|---|
| Linear formula | Cl2C6H3COCl |
| Assay | 99% |
| Boiling point | 142-143 °C/21 mmHg(lit.) |
| Density | 1.462 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.560(lit.) |
| Application | 2,6-Dichlorobenzoyl chloride was used:• in substrate activity screening method for the rapid development of novel substrates and their conversion into non-peptidic inhibitors of Cys and Ser proteases1• in the synthesis of 1-acyliridoles2• in enantiocontrolled total synthesis of (-)-aspicilin3 |
| Melting point | 15-17 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,6-Dichlorobenzoyl chloride used for?
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2,6-Dichlorobenzoyl chloride is used in substrate activity screening for novel protease inhibitors, in the synthesis of 1-acyliridoles, and in enantiocontrolled total synthesis.
What are the CAS number and formula for 2,6-Dichlorobenzoyl chloride?
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The CAS number is 4659-45-4 and the linear formula is Cl₂C₆H₃COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,6-Dichlorobenzoyl chloride with an assay of 99%. This is a technical grade and TSS does not represent it as USP/BP/EP.
How should 2,6-Dichlorobenzoyl chloride be handled safely?
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2,6-Dichlorobenzoyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including full-face protection, gloves, and respiratory protection, in a well-ventilated area. Refer to the safety data sheet for comprehensive handling information.
Is 2,6-Dichlorobenzoyl chloride available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,6-Dichlorobenzoyl chloride.
How can I request a quote or sample for 2,6-Dichlorobenzoyl chloride?
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To request a quote or sample, please contact our sales team through the website or by phone. Our experts will be pleased to assist you.
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