2,5-Dichlorophenylboronic acid
2,5-Dichlorophenylboronic acid (CAS: 135145-90-3) is a disubstituted aryl boronic acid, a versatile building block in organic synthesis. With a molecular weight of 190.82 g/mol, it functions as a key reactant in various catalytic coupling reactions, including Suzuki-Miyaura couplings, and is employed in regioselective iodinations and carbonylative cyclizations. It is a crucial intermediate for the synthesis of complex organic molecules.
- IUPAC
- 2,5-Dichlorobenzeneboronic acid
- Synonyms
- 2,5-Dichlorobenzeneboronic acid
Suzuki-Miyaura Coupling
Serves as a valuable coupling partner in Palladium-catalyzed Suzuki-Miyaura reactions for the formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds.
Regioselective Iodination
Acts as a reactant in regioselective iodination processes, often utilising silver salts, to introduce iodine atoms at specific positions within organic structures.
Carbonylative Cyclization
Participates in Rhodium(I)-catalyzed carbonylative cyclization reactions with alkynes, facilitating the construction of cyclic organic frameworks.
Copper-Catalyzed Coupling
Utilised in copper-catalyzed coupling reactions, expanding its utility in various synthetic transformations for creating new molecular architectures.
| Molecular weight | 190.82 |
|---|---|
| Linear formula | Cl2C6H3B(OH)2 |
| Application | Reactant for:• Regioselective iodination using silver salts1• Pd-catalyzed Suzuki-Miyaura coupling2• Rhodium(I)-catalyzed carbonylative cyclization of alkynes3• Copper catalyzed coupling reactions4 |
| Melting point | 150 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,5-Dichlorophenylboronic acid primarily used for?
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2,5-Dichlorophenylboronic acid is primarily used as a reactant in organic synthesis, particularly in Palladium-catalyzed Suzuki-Miyaura coupling reactions, regioselective iodinations, and rhodium-catalyzed carbonylative cyclizations.
What are the CAS number and formula for 2,5-Dichlorophenylboronic acid?
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The CAS number for 2,5-Dichlorophenylboronic acid is 135145-90-3, and its linear formula is Cl2C6H3B(OH)2.
What grade and purity does Tech Serve Solutions supply for 2,5-Dichlorophenylboronic acid?
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Tech Serve Solutions supplies 2,5-Dichlorophenylboronic acid as a research or technical grade chemical. We do not represent it as USP, BP, or EP grade.
How should 2,5-Dichlorophenylboronic acid be handled safely?
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Handling 2,5-Dichlorophenylboronic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified with WGK Germany rating 3.
Is 2,5-Dichlorophenylboronic acid a controlled substance?
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The provided data does not indicate that 2,5-Dichlorophenylboronic acid is a controlled substance.
How is 2,5-Dichlorophenylboronic acid typically shipped and exported by TSS?
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Tech Serve Solutions, as a specialist global supplier, securely packages and exports chemicals like 2,5-Dichlorophenylboronic acid, adhering to international shipping regulations.
How can I request a sample or a quote for 2,5-Dichlorophenylboronic acid?
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To request a sample or a quote for 2,5-Dichlorophenylboronic acid, please contact our sales department through the provided channels on the Tech Serve Solutions website.
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