2,4-Dinitrobenzenesulfenyl chloride

CAS 528-76-7(O2N)2C6H3SClChemical Synthesis

2,4-Dinitrobenzenesulfenyl chloride (CAS: 528-76-7) is a sulfur-containing organic compound with the linear formula (O₂N)₂C₆H₃SCl and a molecular weight of 234.62 g/mol. This reagent is primarily utilised as a building block in chemical synthesis, particularly for protein modification and structural analysis. Its ability to react selectively with amino acid residues makes it valuable in proteomics research.

IUPAC: 2,4-Dinitrophenylsulfenyl chloride,Kharasch reagent
Synonyms: (O2N)2C6H3SCl2,4-Dinitrophenylsulfenyl chlorideKharasch reagent

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2,4-Dinitrobenzenesulfenyl chloride ((O2N)2C6H3SCl) — chemical structure, CAS 528-76-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Building BlocksChemical SynthesisMolecular BiologyOrganic Building BlocksProtein ModificationProtein Structural AnalysisProteomicsSulfenyl HalidesSulfur Compounds More...

01 /Applications

Chemical Synthesis

This compound serves as a crucial building block in organic synthesis. It has been specifically employed in the preparation of chlorine and bromine biphenyls, demonstrating its utility in halogenation reactions.

Protein Modification and Analysis

2,4-Dinitrobenzenesulfenyl chloride is a reagent for modifying specific amino acid residues within proteins. Its applications extend to protein structural analysis and proteomics, aiding in the characterisation of protein function.

Reagent for Tryptophan Modification

The compound is recognised for its role in the specific modification of tryptophan residues. This targeted reactivity is essential for biochemical studies and the investigation of protein interactions.

02 /Properties

Molecular weight	234.62
Linear formula	(O2N)2C6H3SCl
Assay	96%
Solubility	benzene: solublediethyl ether: solubleethylene chloride: solubleglacial acetic acid: solublemethylene chloride: solubletrichloroethylene: solublexylene: soluble
Storage temperature	2-8°C
Application	2,4-Dinitrobenzenesulfenyl chloride was used in preparation of chlorine and bromine biphenyls1.
Melting point	94-97 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 3261 8 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	C
Risk statements (R)	34-37
Safety statements (S)	26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

528-76-7

MDL number

MFCD00007129

PubChem substance

24846698

Beilstein registry

405600

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,4-Dinitrobenzenesulfenyl chloride used for?

2,4-Dinitrobenzenesulfenyl chloride is used as a building block in chemical synthesis, for protein modification and structural analysis, and as a reagent for tryptophan modification. It has also been used in the preparation of chlorine and bromine biphenyls.

What is the CAS number and chemical formula for 2,4-Dinitrobenzenesulfenyl chloride?

The CAS number is 528-76-7 and the linear formula is (O₂N)₂C₆H₃SCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2,4-Dinitrobenzenesulfenyl chloride with an assay of 96%. We do not represent this product as USP, BP, or EP grade.

How should 2,4-Dinitrobenzenesulfenyl chloride be handled safely?

This compound is corrosive and may cause severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection. Store at 2-8°C.

How is 2,4-Dinitrobenzenesulfenyl chloride packed and shipped?

This product is classified under UN 3261, 8 / PG II, indicating it is a corrosive solid. It is packed and shipped in accordance with international regulations for hazardous materials.

How can I request a sample or quote for 2,4-Dinitrobenzenesulfenyl chloride?

To request a sample or a quote, please contact our sales department via the website or by phone, providing your contact details and the product CAS number (528-76-7).