2,4-Dichlorobenzoyl chloride
2,4-Dichlorobenzoyl chloride (CAS: 89-75-8), with the linear formula Cl2C6H3COCl and a molecular weight of 209.46 g/mol, is an acid halide used in organic synthesis. This compound serves as a key building block for creating more complex molecules. Its reactivity makes it valuable for acylation reactions and for constructing biaryl compounds through methods like Suzuki coupling. Tech Serve Solutions supplies this reagent for research and development purposes.
- Synonyms
- Cl2C6H3COCl
Suzuki Coupling Reagent
2,4-Dichlorobenzoyl chloride is employed in the synthesis of biaryl compounds, a significant transformation in organic chemistry, utilising palladium-catalysed cross-coupling reactions like the Suzuki coupling.
Acylation Agent
This acid halide functions as an effective acylating agent in the synthesis of various organic molecules, including the preparation of potent non-sarcosine-derived Gly T1 inhibitors.
Organic Synthesis Building Block
As a versatile organic building block, 2,4-Dichlorobenzoyl chloride provides a dichlorinated benzoyl moiety for incorporation into diverse molecular frameworks during complex synthesis.
| Molecular weight | 209.46 |
|---|---|
| Linear formula | Cl2C6H3COCl |
| Assay | ≥97.0% (GC) |
| Boiling point | 150 °C/34 mmHg(lit.) |
| Density | 1.494 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.592(lit.)n20/D 1.593 |
| Application | 2,4-Dichlorobenzoyl chloride was used in the synthesis of biaryls by following the Suzuki coupling1. It was used for acylation in the synthesis of potent non-sarcosine-derived Gly T1 inhibitors2. |
| Melting point | 16-18 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 137 °C / 278.6 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dichlorobenzoyl chloride used for?
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2,4-Dichlorobenzoyl chloride is primarily used as a building block in organic synthesis, specifically for acylation reactions and in the synthesis of biaryl compounds via Suzuki coupling.
What is the CAS number and formula for 2,4-Dichlorobenzoyl chloride?
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The CAS number for 2,4-Dichlorobenzoyl chloride is 89-75-8, and its linear formula is Cl2C6H3COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Dichlorobenzoyl chloride with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should 2,4-Dichlorobenzoyl chloride be handled safely?
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2,4-Dichlorobenzoyl chloride is dangerous. It causes severe skin burns and eye damage (H314) and may cause respiratory irritation (H335). Handle with extreme care, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection in a well-ventilated area. Refer to the safety data sheet for full guidance.
Is 2,4-Dichlorobenzoyl chloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2,4-Dichlorobenzoyl chloride, subject to relevant shipping regulations.
How can I request a sample or quote for 2,4-Dichlorobenzoyl chloride?
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To request a sample or a quote for 2,4-Dichlorobenzoyl chloride, please use the contact form on our website or reach out to our sales team directly with your requirements.
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