2,4-Dichloro-6-methylpyrimidine
2,4-Dichloro-6-methylpyrimidine (CAS 5424-21-5), with the molecular formula C5H4Cl2N2 and a molecular weight of 163.00 g/mol, is a halogenated heterocyclic compound. It serves as a valuable building block in organic synthesis, particularly in the construction of more complex molecules within the pharmaceutical and chemical industries. This compound is characterised by its pyrimidine core functionalised with two chlorine atoms and a methyl group.
- Synonyms
- C5H4Cl2N22,4-Dichloropyrimidine, 6-methyl-
Synthesis of Amine Derivatives
2,4-Dichloro-6-methylpyrimidine is utilized in the synthesis of complex amine structures. For example, it has been employed in the preparation of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine, showcasing its utility in creating novel heterocyclic compounds.
Pharmaceutical Intermediate
As a key building block, this dichlorinated pyrimidine derivative facilitates the development of potential pharmaceutical agents. Its structure allows for further chemical modifications to create diverse molecular scaffolds relevant to drug discovery.
Chemical Research and Development
This compound is employed in various chemical synthesis pathways, serving as a versatile reagent for researchers exploring new chemical entities and reactions. Its reactivity profile makes it useful for introducing the methylpyrimidine moiety into target molecules.
| Molecular weight | 163.00 |
|---|---|
| Empirical formula | C5H4Cl2N2 |
| Assay | 98% |
| Boiling point | 219 °C(lit.) |
| Application | 2,4-Dichloro-6-methylpyrimidine was used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine1. |
| Melting point | 44-47 °C(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3263 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dichloro-6-methylpyrimidine used for?
+
2,4-Dichloro-6-methylpyrimidine is primarily used as a building block in organic synthesis, including the preparation of amine derivatives and as an intermediate in pharmaceutical research and development.
What are the CAS number and molecular formula?
+
The CAS number for 2,4-Dichloro-6-methylpyrimidine is 5424-21-5, and its molecular formula is C5H4Cl2N2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2,4-Dichloro-6-methylpyrimidine with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for handling 2,4-Dichloro-6-methylpyrimidine?
+
This compound is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, must be used. Handle with extreme caution in a well-ventilated area.
How is 2,4-Dichloro-6-methylpyrimidine packed, shipped, and exported?
+
2,4-Dichloro-6-methylpyrimidine is carefully packed according to international shipping regulations, including UN 3263 8/PGII classification, for safe global export.
How can I request a quote or sample?
+
To request a quote or sample of 2,4-Dichloro-6-methylpyrimidine, please contact the Tech Serve Solutions sales team through our website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis