2,4-Dichloro-5-nitropyrimidine
2,4-Dichloro-5-nitropyrimidine (CAS: 49845-33-2) is a halogenated heterocyclic organic compound with the molecular formula C4HCl2N3O2 and a molecular weight of 193.98 g/mol. This chemical building block is primarily utilised as an intermediate in organic synthesis, particularly in the development of purine derivatives. Its reactive chlorine atoms and nitro group make it a versatile reagent for introducing the pyrimidine core into more complex molecules.
- Synonyms
- C4HCl2N3O2
Intermediate in Diaminopurine Synthesis
2,4-Dichloro-5-nitropyrimidine serves as a key intermediate in the solid-phase synthesis of diaminopurines. This application highlights its utility in constructing complex heterocyclic structures relevant to medicinal chemistry.
Heterocyclic Building Block
As a halogenated pyrimidine derivative, this compound is a valuable building block in organic synthesis. It can be employed to introduce substituted pyrimidine rings into various target molecules.
Chemical Synthesis Reagent
The presence of reactive chlorine atoms allows for nucleophilic substitution reactions, making 2,4-Dichloro-5-nitropyrimidine a useful reagent for creating novel chemical entities and functionalised heterocycles.
| Molecular weight | 193.98 |
|---|---|
| Empirical formula | C4HCl2N3O2 |
| Assay | 97% |
| Boiling point | 0.9 °C/0.5 mmHg |
| Application | Intermediate in a solid-phase synthesis of diaminopurines.1 |
| Melting point | 28-32 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dichloro-5-nitropyrimidine used for?
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2,4-Dichloro-5-nitropyrimidine is primarily used as an intermediate in the solid-phase synthesis of diaminopurines and as a general building block in chemical synthesis.
What is the CAS number and formula for 2,4-Dichloro-5-nitropyrimidine?
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The CAS number is 49845-33-2 and the empirical formula (Hill notation) is C4HCl2N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Dichloro-5-nitropyrimidine with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2,4-Dichloro-5-nitropyrimidine be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation as it may cause skin irritation, eye irritation, and respiratory irritation (H315-H319-H335).
Is this product shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a quote or sample?
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Please contact our sales team directly through our website or provide your details to request a quote or sample of 2,4-Dichloro-5-nitropyrimidine.
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