2,4-Dichloro-5-methylpyrimidine
2,4-Dichloro-5-methylpyrimidine (CAS: 1780-31-0) is a halogenated heterocyclic compound with the molecular formula C5H4Cl2N2 and a molecular weight of 163.00 g/mol. It serves as a valuable building block in organic synthesis, particularly for the construction of pyrimidine derivatives. Its chemical structure allows for diverse functionalisation, making it an important intermediate in the development of new chemical entities within research and industrial applications.
- Synonyms
- C5H4Cl2N2

Organic Synthesis Intermediate
Utilised as a key intermediate in multi-step organic synthesis pathways. The two chlorine atoms offer reactive sites for nucleophilic substitution reactions, facilitating the introduction of various functional groups onto the pyrimidine core.
Heterocyclic Chemistry
A fundamental building block for constructing more complex heterocyclic systems. It is employed in the synthesis of novel compounds with potential applications in medicinal chemistry and material science.
Research and Development
Essential reagent in academic and industrial research laboratories for exploring new synthetic methodologies and discovering novel chemical structures.
| Molecular weight | 163.00 |
|---|---|
| Empirical formula | C5H4Cl2N2 |
| Assay | 98% |
| Boiling point | 108-109 °C/11 mmHg(lit.) |
| Density | 1.39 g/mL at 25 °C(lit.) |
| Melting point | 26-28 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4-Dichloro-5-methylpyrimidine (CAS: 1780-31-0) used for?
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2,4-Dichloro-5-methylpyrimidine (CAS: 1780-31-0) is primarily used as a building block and intermediate in organic synthesis, particularly for the creation of more complex pyrimidine derivatives and heterocyclic compounds in research and development.
What are the CAS number and chemical formula for 2,4-Dichloro-5-methylpyrimidine?
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The CAS number for 2,4-Dichloro-5-methylpyrimidine is 1780-31-0, and its empirical formula is C5H4Cl2N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4-Dichloro-5-methylpyrimidine with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
How should 2,4-Dichloro-5-methylpyrimidine be handled safely?
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2,4-Dichloro-5-methylpyrimidine is classified as Danger (GHS05) with hazard statement H314, indicating it causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, is mandatory during handling. Refer to the safety data sheet for comprehensive guidance.
How is 2,4-Dichloro-5-methylpyrimidine packed and exported?
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2,4-Dichloro-5-methylpyrimidine is carefully packed to ensure safe transit and is available for global export. Specific packaging details comply with international shipping regulations for hazardous materials (UN 3261 8 / PGII).
How can I request a sample or quote for 2,4-Dichloro-5-methylpyrimidine?
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To request a sample or a quotation for 2,4-Dichloro-5-methylpyrimidine, please contact our sales department via the website or direct email, providing your specific requirements.
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