2,4,6-Trimethylpyridine
2,4,6-Trimethylpyridine (CAS: 108-75-8), a clear, colourless to yellow liquid, is a pyridine derivative with a molecular weight of 121.18 g/mol. It is recognised for its use as a tissue fixative in electron microscopy. As a key building block in chemical synthesis, it is particularly valuable in the realm of heterocyclic chemistry. Tech Serve Solutions supplies this compound with a high purity of ≥98.0%.
- IUPAC
- 2,4,6-Collidine,sym-Collidine
- Synonyms
- 108-75-8C8H11N2,4,6-Collidinesym-Collidine

Tissue Fixation
This compound serves as an effective tissue fixative, specifically utilised in electron microscopy techniques. Its properties aid in preserving cellular structures for detailed examination.
Chemical Synthesis Intermediate
As a versatile building block, 2,4,6-Trimethylpyridine is employed in various chemical synthesis pathways. It is a valuable reagent for creating more complex organic molecules, especially within heterocyclic chemistry.
Research and Development
Utilised in laboratory settings for research purposes, this chemical contributes to the development of new compounds and methodologies. Its defined purity ensures reliable experimental outcomes.
| Molecular weight | 121.18 |
|---|---|
| Empirical formula | C8H11N |
| Assay | ≥98.0% (GC) |
| Boiling point | 171-172 °C(lit.) |
| Density | 0.914 g/mL at 20 °C0.917 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.498(lit.)n20/D 1.498 |
| Storage temperature | 2-8°C |
| Melting point | −43 °C(lit.) |
| Impurities tested | ≤0.1% water |
| Application | Tissue fixative for electron microscopy. |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 55 °C / 131 °F |
| Transport (UN / ADR) | UN 1992 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 10-20/21/22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Evapn Residue | ≤0.1% |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4,6-Trimethylpyridine primarily used for?
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2,4,6-Trimethylpyridine is primarily used as a tissue fixative for electron microscopy and as a building block in chemical synthesis, particularly in heterocyclic chemistry.
What is the CAS number and molecular formula for 2,4,6-Trimethylpyridine?
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The CAS number for 2,4,6-Trimethylpyridine is 108-75-8, and its empirical formula is C8H11N.
What grade and purity does Tech Serve Solutions supply for 2,4,6-Trimethylpyridine?
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Tech Serve Solutions supplies 2,4,6-Trimethylpyridine with a purity of ≥98.0% (GC). This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should 2,4,6-Trimethylpyridine be handled safely?
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2,4,6-Trimethylpyridine is a hazardous substance. It is flammable, harmful if swallowed or inhaled, causes skin irritation, and serious eye irritation. Handle with appropriate personal protective equipment, including gloves, eyeshields, and a respirator, in a well-ventilated area. Refer to the safety data sheet for comprehensive handling guidelines.
How is 2,4,6-Trimethylpyridine packed, shipped, and exported?
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2,4,6-Trimethylpyridine is carefully packed according to international shipping regulations for hazardous materials. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide.
How can I request a quote or sample for 2,4,6-Trimethylpyridine?
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To request a quote or a sample of 2,4,6-Trimethylpyridine, please contact the Tech Serve Solutions sales team via our website or directly by phone.
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