2,3-Dichlorobenzonitrile
2,3-Dichlorobenzonitrile (CAS: 6574-97-6) is an organic compound with the linear formula Cl2C6H3CN and a molecular weight of 172.01 g/mol. This chemical serves as a valuable intermediate and building block in organic synthesis. It is particularly noted for its use in reactions such as nucleophilic aromatic fluorination, reactions with magnesium amides for carboxamide synthesis, and as a participant in Suzuki-Miyaura coupling reactions, contributing to the development of diverse chemical structures.
- IUPAC
- 2,3-Dichlorophenyl cyanide
- Synonyms
- 2,3-Dichlorophenyl cyanide
Nucleophilic Aromatic Fluorination
2,3-Dichlorobenzonitrile can function as a substrate in nucleophilic aromatic substitution reactions to introduce fluorine atoms into aromatic systems. This transformation is crucial for synthesizing fluorinated organic molecules with unique properties.
Carboxamide Synthesis
The compound reacts with magnesium amides, facilitating the synthesis of carboxamides. This application is significant in the preparation of amide-containing compounds used in various chemical and pharmaceutical industries.
Suzuki-Miyaura Coupling Reactions
2,3-Dichlorobenzonitrile is employed as a coupling partner in Suzuki-Miyaura reactions. This palladium-catalysed cross-coupling is a powerful method for forming carbon-carbon bonds, enabling the construction of complex organic frameworks.
| Molecular weight | 172.01 |
|---|---|
| Linear formula | Cl2C6H3CN |
| Application | Reactant involved in:• Nucleophilic aromatic fluorination1• Reactions with magnesium amides for synthesis of carboxamides2• Suzuki-Miyaura coupling reactions3 |
| Melting point | 60-64 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 22-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,3-Dichlorobenzonitrile used for?
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2,3-Dichlorobenzonitrile is used as a reactant in nucleophilic aromatic fluorination, reactions with magnesium amides for carboxamide synthesis, and Suzuki-Miyaura coupling reactions. It functions as a versatile building block in organic synthesis.
What are the CAS number and formula for 2,3-Dichlorobenzonitrile?
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The CAS number for 2,3-Dichlorobenzonitrile is 6574-97-6 and its linear formula is Cl2C6H3CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,3-Dichlorobenzonitrile. The specific assay and grade are detailed on the product's specification sheet. We do not represent this product as USP, BP, or EP grade.
How should 2,3-Dichlorobenzonitrile be handled safely?
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2,3-Dichlorobenzonitrile is classified with GHS07 symbol and a Warning signal word. It has hazard statements H302, H312, and H332, indicating it is harmful if swallowed, in contact with skin, and if inhaled. Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, in a well-ventilated area.
Is 2,3-Dichlorobenzonitrile exported by Tech Serve Solutions?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,3-Dichlorobenzonitrile.
How can I request a quote or sample for 2,3-Dichlorobenzonitrile?
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To request a quote or sample of 2,3-Dichlorobenzonitrile, please contact the Tech Serve Solutions sales department through our website or by phone.
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