(−)-2,3-Bis[(2R,5R)-2,5-dimethylphospholano]maleic anhydride
(−)-2,3-Bis[(2R,5R)-2,5-dimethylphospholano]maleic anhydride (CAS 505092-86-4) is a chiral ligand with the molecular formula C16H24O3P2 and a molecular weight of 326.31. This compound is a specialised reagent employed in asymmetric synthesis, particularly as a ligand in catalytic processes. It is valued for its specific stereochemical properties, enabling enantioselective transformations crucial in the fine chemical and pharmaceutical industries.
- IUPAC
- 3,4-Bis[(2R,5R)-2,5-dimethyl-1-phospholanyl]furan-2,5-dione,catASium® M(R)
- Synonyms
- 505092-86-4, C16H24O3P2, 3,4-Bis[(2R,5R)-2,5-dimethyl-1-phospholanyl]furan-2,5-dione, catASium® M(R)
![(−)-2,3-Bis[(2R,5R)-2,5-dimethylphospholano]maleic anhydride (5R)-2) — chemical structure, CAS 505092-86-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F505092-86-4.png&w=3840&q=75)
Asymmetric Hydrogenation Catalysis
This phospholane-based ligand is recognised for its application in asymmetric hydrogenation reactions. It can form complexes with transition metals, acting as a chiral catalyst to promote the enantioselective reduction of various substrates.
Chiral Ligand in Synthesis
As a privileged ligand, it plays a role in developing stereoselective synthetic routes. Its unique structure facilitates the creation of chiral molecules with high enantiomeric excess, essential for pharmaceutical intermediates.
Precursor for Metal Complexes
The compound serves as a building block for synthesising custom metal complexes used in catalysis. These complexes are designed to achieve specific catalytic activities and selectivities in organic transformations.
| Molecular weight | 326.31 |
|---|---|
| Empirical formula | C16H24O3P2 |
| Assay | ≥98% (31P-NMR)98% |
| Application | Essential Elements for Asymmetric Hydrogenations |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-2,3-Bis[(2R,5R)-2,5-dimethylphospholano]maleic anhydride used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis, particularly in asymmetric hydrogenation reactions and for creating enantioselective catalysts.
What are the CAS number and formula for this chemical?
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The CAS number is 505092-86-4 and the empirical formula (Hill Notation) is C16H24O3P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥98% (by 31P-NMR) or 98%. This is a technical or research grade, and TSS does not represent it as meeting USP, BP, or EP pharmacopoeial standards.
How should (–)-2,3-Bis[(2R,5R)-2,5-dimethylphospholano]maleic anhydride be handled?
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When handling this compound, appropriate personal protective equipment must be used, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany as 3, indicating a hazard to water.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions, a global supplier since 1998, professionally packs, ships, and exports chemicals worldwide, adhering to all relevant international regulations for safe transport.
How can I request a sample or quote for this product?
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To request a sample or a quotation for (–)-2,3-Bis[(2R,5R)-2,5-dimethylphospholano]maleic anhydride, please contact our sales department through the TSS website or by phone.
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