2-(2-Hydroxyethoxy)phenol
2-(2-Hydroxyethoxy)phenol (CAS: 4792-78-3) is a valuable organic building block with the linear formula HOCH₂CH₂OC₆H₄OH and a molecular weight of 154.16 g/mol. This compound serves as a key intermediate in the synthesis of complex molecules. Its structure, featuring both phenolic and ether functionalities along with a primary alcohol, makes it suitable for creating macrocyclic compounds and specialized ionophores, facilitating advanced chemical research and development.

Synthesis of Macrocyclic Compounds
This phenol derivative is utilised in the preparation of macrocyclic lipophilic benzocrown ethers. These compounds are significant in host-guest chemistry and molecular recognition studies.
Development of Ionophores
It is employed in the creation of coiled synthetic carboxylic ionophores. These molecules exhibit selective binding capabilities, such as encapsulating potassium ions, and are critical for ion sensing applications.
Organic Synthesis Intermediate
As a versatile building block, 2-(2-Hydroxyethoxy)phenol is used in various organic synthesis pathways. Its functional groups allow for diverse chemical transformations in academic and industrial research.
| Molecular weight | 154.16 |
|---|---|
| Linear formula | HOCH2CH2OC6H4OH |
| Assay | 98% |
| Boiling point | 128 °C/0.7 mmHg(lit.) |
| Application | 2-(2-Hydroxyethoxy)phenol was used in the preparation of:• macrocyclic lipophilic benzocrown ethers1• coiled synthetic carboxylic ionophore with eight ether oxygens and five aromatic rings capable of encapsulating potassium ion2 |
| Melting point | 99-100 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(2-Hydroxyethoxy)phenol used for?
+
2-(2-Hydroxyethoxy)phenol is used as a building block in organic synthesis, notably in the preparation of macrocyclic lipophilic benzocrown ethers and coiled synthetic carboxylic ionophores for applications like potassium ion encapsulation.
What is the CAS number and formula for 2-(2-Hydroxyethoxy)phenol?
+
The CAS number for 2-(2-Hydroxyethoxy)phenol is 4792-78-3, and its linear formula is HOCH₂CH₂OC₆H₄OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 2-(2-Hydroxyethoxy)phenol with a purity of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-(2-Hydroxyethoxy)phenol be handled safely?
+
Based on GHS data, 2-(2-Hydroxyethoxy)phenol is a warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, in a well-ventilated area.
Can Tech Serve Solutions export 2-(2-Hydroxyethoxy)phenol?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-(2-Hydroxyethoxy)phenol.
How can I request a quote or sample for 2-(2-Hydroxyethoxy)phenol?
+
To request a quote or sample, please contact our sales department through the website or by phone, providing the product name and CAS number (4792-78-3).
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis