2-(2-Aminoethyl)-1,3-di-Boc-guanidine
2-(2-Aminoethyl)-1,3-di-Boc-guanidine (CAS: 203258-44-0) is a protected guanidine derivative with the molecular formula C13H26N4O4 and a molecular weight of 302.37 g/mol. This compound serves as a valuable building block in chemical synthesis and peptide chemistry. Its primary utility lies in guanidine protection and guanidinylation reactions, facilitating complex organic transformations.
- IUPAC
- 1,3-Di-Boc-2-(2-aminoethyl)guanidine
- Synonyms
- 1,3-Di-Boc-2-(2-aminoethyl)guanidine

Guanidine Protection
The di-Boc protecting groups on the guanidine moiety allow for controlled reactivity. This is crucial in multi-step syntheses where selective modification of other functional groups is required before deprotection.
Peptide Synthesis
As a protected guanidine, this compound can be incorporated into peptide chains to introduce a guanidino group, mimicking the side chain of arginine. This is vital for studying peptide function and developing peptide-based therapeutics.
Chemical Synthesis
This reagent is employed in diverse organic synthesis pathways, enabling the introduction of functionalised guanidine units into target molecules. Its protected nature simplifies reaction planning and execution.
Chemical Biology
In chemical biology research, 2-(2-Aminoethyl)-1,3-di-Boc-guanidine can be used to synthesise labelled or modified peptides and small molecules for probing biological pathways and interactions.
| Molecular weight | 302.37 |
|---|---|
| Empirical formula | C13H26N4O4 |
| Assay | ≥90% (HPLC) |
| Grade | technical |
| Storage temperature | −20°C |
| Melting point | 95-98 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Shipped In | dry ice |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(2-Aminoethyl)-1,3-di-Boc-guanidine used for?
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This compound is primarily used in chemical synthesis, peptide chemistry, and chemical biology for guanidine protection and guanidinylation reactions. It acts as a building block for introducing protected guanidine functionalities into organic molecules.
What is the CAS number and molecular formula for 2-(2-Aminoethyl)-1,3-di-Boc-guanidine?
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The CAS number is 203258-44-0, and the empirical formula (Hill notation) is C13H26N4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product in technical grade with an assay of ≥90% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 2-(2-Aminoethyl)-1,3-di-Boc-guanidine be handled and stored?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at -20°C.
How is 2-(2-Aminoethyl)-1,3-di-Boc-guanidine shipped?
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This product is shipped in dry ice to maintain its stability during transit.
How can I request a quote or sample?
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Please contact our sales team or use the online inquiry form to request a quote or sample of 2-(2-Aminoethyl)-1,3-di-Boc-guanidine.
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