(1R, 2R)-Pseudoephedrine-(S)-2-methylhydrocinnamamide
(1R, 2R)-Pseudoephedrine-(S)-2-methylhydrocinnamamide (CAS: 352530-53-1) is a chiral compound with a molecular weight of 311.42 g/mol. This ephedrine derivative is primarily utilised as a chiral auxiliary in asymmetric synthesis. Its specific stereochemistry makes it valuable for controlling the stereochemical outcome of chemical reactions, enabling the selective formation of desired enantiomers in complex organic molecules.
- Synonyms
- C20H25NO2

Asymmetric Synthesis
As a chiral auxiliary, it can be employed to direct the stereoselective synthesis of complex organic molecules. Its well-defined stereochemistry is crucial for inducing chirality in reaction products.
Chiral Auxiliaries
This compound serves as a valuable tool in stereoselective transformations, facilitating the creation of enantiomerically enriched compounds. It is particularly useful in reactions where precise control over stereochemistry is required.
Ephedrine Derivative Chemistry
As an ephedrine derivative, it may find applications in research exploring the reactivity and synthetic utility of related chiral structures. This can lead to novel methodologies in organic synthesis.
| Molecular weight | 311.42 |
|---|---|
| Empirical formula | C20H25NO2 |
| Assay | 97% |
| Optical activity | [α]20/D −16°, c = 1 in chloroform |
| Optical purity | ee: 99% (HPLC) |
| Melting point | 136-140 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R, 2R)-Pseudoephedrine-(S)-2-methylhydrocinnamamide used for?
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(1R, 2R)-Pseudoephedrine-(S)-2-methylhydrocinnamamide is primarily used as a chiral auxiliary in asymmetric synthesis to control the stereochemical outcome of chemical reactions.
What is the CAS number and formula for this compound?
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The CAS number is 352530-53-1 and the empirical formula (Hill notation) is C20H25NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of 97% and optical purity of ee: 99% (HPLC). It is not supplied as USP, BP, or EP grade.
How should (1R, 2R)-Pseudoephedrine-(S)-2-methylhydrocinnamamide be handled?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK 2 in Germany.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and can export (1R, 2R)-Pseudoephedrine-(S)-2-methylhydrocinnamamide.
How can I request a sample or quote?
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Please contact our sales team directly through our website or by phone to request a sample or a formal quotation for (1R, 2R)-Pseudoephedrine-(S)-2-methylhydrocinnamamide.
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