(1R,2R)-2-(Diphenylphosphino)cyclohexylamine
(1R,2R)-2-(Diphenylphosphino)cyclohexylamine (CAS 452304-59-5) is a chiral phosphine ligand with a molecular weight of 283.35 g/mol. Its unique structure makes it valuable in asymmetric catalysis. Supplied at a minimum 96% assay, this compound is an important building block for complex synthesis in both academic research and industrial applications requiring precise stereochemical control.
- IUPAC
- (1R,2R)-2-(Diphenylphosphino)cyclohexanamine
- Synonyms
- C18H22NP(1R,2R)-2-(Diphenylphosphino)cyclohexanamine

Asymmetric Catalysis
Serves as a chiral ligand in transition metal-catalysed asymmetric reactions, facilitating the synthesis of enantiomerically enriched products.
Homogeneous Catalysis
Utilised as a component in homogeneous catalytic systems for various organic transformations, influencing reaction rates and selectivity.
Pharmaceutical Intermediate Synthesis
A key intermediate in the development and production of complex pharmaceutical compounds where stereochemistry is critical.
Organometallic Chemistry
Employed in studies and applications involving organometallic complexes, particularly those requiring phosphine coordination.
| Molecular weight | 283.35 |
|---|---|
| Empirical formula | C18H22NP |
| Assay | 96% |
| Optical activity | [α]22/D -79°, c = 0.5% in chloroform |
| Melting point | 43-48 °C |
| Transport (UN / ADR) | UN 3335 |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-2-(Diphenylphosphino)cyclohexylamine used for?
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(1R,2R)-2-(Diphenylphosphino)cyclohexylamine is primarily used as a chiral ligand in asymmetric catalysis and in homogeneous catalysis for various organic transformations. It also serves as a valuable intermediate in the synthesis of complex pharmaceutical compounds.
What is the CAS number and molecular formula for this compound?
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The CAS number is 452304-59-5, and its empirical formula is C18H22NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (1R,2R)-2-(Diphenylphosphino)cyclohexylamine with a minimum assay of 96%. This compound is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
What are the safety and handling considerations for this product?
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This compound is classified under UN 3335 and has a WGK Germany rating of 3. It is typically handled with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling and hazard information.
How is this chemical packed and shipped?
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Tech Serve Solutions packs and exports fine chemicals with adherence to all relevant international shipping and handling regulations to ensure safe and secure delivery worldwide.
How can I request a sample or quote for (1R,2R)-2-(Diphenylphosphino)cyclohexylamine?
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To request a sample or a quote, please visit the product page on the Tech Serve Solutions website and use the contact form or contact our sales team directly.
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