(1R,2R)-2-Amino-1-phenylpropyldiphenylphosphine
(1R,2R)-2-Amino-1-phenylpropyldiphenylphosphine (CAS 799297-44-2) is a chiral phosphine compound with a molecular weight of 319.38. This optically active molecule, with a specific rotation of [α]/D -138.0°, is primarily utilised as a ligand in asymmetric catalysis. Its diphenylphosphine moiety and chiral amino-phenylpropyl backbone make it valuable for mediating stereoselective transformations in organic synthesis, particularly in the development of enantiomerically pure compounds.
- Synonyms
- C21H22NP
Asymmetric Catalysis Ligand
This compound serves as a chiral phosphine ligand in transition metal catalysis. It is designed to facilitate enantioselective reactions, enabling the synthesis of chiral molecules with high optical purity.
Organometallic Synthesis
As a phosphine derivative, it can be employed in the synthesis of organometallic complexes. These complexes often exhibit unique catalytic properties or serve as precursors in further chemical transformations.
Stereoselective Transformations
The chiral nature of the molecule makes it instrumental in guiding stereoselective reactions, leading to the preferential formation of one stereoisomer over others, crucial in pharmaceutical and fine chemical synthesis.
| Molecular weight | 319.38 |
|---|---|
| Empirical formula | C21H22NP |
| Optical activity | [α]/D -138.0°, c = 0.5% in chloroform |
| Storage temperature | 20-25°C |
| Melting point | 105-109 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3263 8 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-2-Amino-1-phenylpropyldiphenylphosphine used for?
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This compound is primarily used as a chiral phosphine ligand in asymmetric catalysis, facilitating stereoselective transformations in organic synthesis.
What is the CAS number and formula for (1R,2R)-2-Amino-1-phenylpropyldiphenylphosphine?
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The CAS number is 799297-44-2 and the empirical formula is C21H22NP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with a molecular weight of 319.38 and an optical activity of [α]/D -138.0°. We do not represent this product as USP, BP, or EP grade.
How should (1R,2R)-2-Amino-1-phenylpropyldiphenylphosphine be handled?
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This compound is classified as a danger with hazard statement H314 (Causes severe skin burns and eye damage). Handle with appropriate personal protective equipment (gloves, eye protection) and seek immediate medical attention if contact occurs, following precautionary statements P280, P305 + P351 + P338, and P310.
How is this chemical exported and shipped by Tech Serve Solutions?
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This chemical is shipped according to UN 3263, Class 8, Packing Group III regulations. Tech Serve Solutions is experienced in global export of chemical reagents.
How can I request a sample or quote for this product?
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Please contact our sales team directly via the website or telephone to request a sample or obtain a quotation for (1R,2R)-2-Amino-1-phenylpropyldiphenylphosphine.
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