1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one
1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one (CAS: 41443-28-1) is a pale yellow powder with a molecular weight of 187.15 g/mol. This heterocyclic compound is recognised for its role as a guanylyl cyclase inhibitor. It serves as a valuable tool in biochemical research, particularly within cell biology and neuroscience, for investigating cellular signaling pathways and cyclic nucleotide metabolism.
- IUPAC
- ODQ
- Synonyms
- 3-a]quinoxalin-1-oneODQ
![1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one (C9H5N3O2) — chemical structure, CAS 41443-28-1; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F41443-28-1.png&w=3840&q=75)
Guanylyl Cyclase Inhibition
This compound is utilised as a selective inhibitor of guanylyl cyclase, a key enzyme involved in intracellular signaling. Its application aids in studying the physiological and pathological roles of cyclic guanosine monophosphate (cGMP).
Cell Signaling Research
As a bioactive small molecule, it is employed in cell signaling research to probe pathways related to nitric oxide and cyclic nucleotides. This helps elucidate mechanisms in areas like neuroscience and cell biology.
Biochemical and Reagent Studies
It functions as a biochemical reagent for in vitro studies investigating enzyme activity and substrate interactions. Its defined properties make it suitable for controlled experimental conditions.
| Molecular weight | 187.15 |
|---|---|
| Empirical formula | C9H5N3O2 |
| Form | powder |
| Colour | pale yellow |
| Solubility | ethanol: soluble1.2 mg/mLDMSO: soluble5 mg/mLH2O: insoluble |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one primarily used for?
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1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one is primarily used as a guanylyl cyclase inhibitor in biochemical and cell signaling research.
What are the CAS number and molecular formula for this compound?
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The CAS number is 41443-28-1, and the empirical formula is C9H5N3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a pale yellow powder. The specific grade and purity available are detailed in the product specifications. We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product data.
How should 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified as an irritant to skin, eyes, and respiratory system (H315, H319, H335).
How is this chemical typically shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, adhering to all relevant shipping and export regulations for chemical products.
How can I request a sample or a quote?
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To request a sample or a quote, please contact our sales department through the provided channels on the Tech Serve Solutions website.
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