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10-Camphorsulfonyl chloride

CAS 4552-50-5C10H15ClO3SChemical Synthesis

10-Camphorsulfonyl chloride (CAS: 4552-50-5), a sulfur compound with the empirical formula C10H15ClO3S and a molecular weight of 250.74 g/mol, is a vital building block in organic synthesis. This sulfonyl halide derivative is primarily employed in chemical transformations for introducing the camphorsulfonyl group into various molecules. Its utility is found in research and development laboratories and in specialised chemical manufacturing processes requiring precise synthetic methodologies.

IUPAC
Camphor-10-sulfonic acid chloride
Synonyms
Camphor-10-sulfonic acid chloride
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10-Camphorsulfonyl chloride (C10H15ClO3S) — chemical structure, CAS 4552-50-5; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisOrganic Building BlocksSulfonyl HalidesSulfur Compounds
01 /Applications

Chiral Auxiliary in Asymmetric Synthesis

10-Camphorsulfonyl chloride can be used to introduce chiral auxiliary groups, facilitating enantioselective synthesis of complex organic molecules. This is crucial in the pharmaceutical industry for producing optically pure drug intermediates.

Reagent in Organic Synthesis

As a functionalised sulfonyl chloride, it serves as an electrophilic reagent for reactions such as sulfonylation of alcohols and amines. These reactions are fundamental steps in the synthesis of diverse organic compounds.

Preparation of Sulfonamides and Sulfonate Esters

It readily reacts with amines to form sulfonamides and with alcohols to yield sulfonate esters. These functional groups are common in medicinal chemistry and material science research.

02 /Properties
Molecular weight250.74
Empirical formulaC10H15ClO3S
Assay98%
Melting point66-68 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Transport (UN / ADR)UN 3261 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-27-28-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
4552-50-5
MDL number
MFCD00064155
PubChem substance
24858221
Beilstein registry
3205975
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 10-Camphorsulfonyl chloride used for?

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10-Camphorsulfonyl chloride is primarily used as a building block and reagent in organic synthesis, particularly for introducing the camphorsulfonyl group, and in the preparation of sulfonamides and sulfonate esters.

What are the CAS number and formula for 10-Camphorsulfonyl chloride?

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The CAS number for 10-Camphorsulfonyl chloride is 4552-50-5, and its empirical formula is C10H15ClO3S.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 10-Camphorsulfonyl chloride with an assay of 98%. We do not represent this product as USP, BP, or EP grade.

How should 10-Camphorsulfonyl chloride be handled safely?

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10-Camphorsulfonyl chloride is a Danger substance (H314) that causes severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, is essential. Always handle in a well-ventilated area.

Is 10-Camphorsulfonyl chloride a controlled substance?

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The provided data does not indicate that 10-Camphorsulfonyl chloride is a controlled substance.

How is 10-Camphorsulfonyl chloride packed and shipped?

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10-Camphorsulfonyl chloride is packed and shipped according to relevant regulations for hazardous materials, identified under UN 3261, Class 8, Packing Group II. We export globally, adhering to all international shipping standards.

How can I request a quote or sample for 10-Camphorsulfonyl chloride?

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To request a quote or sample for 10-Camphorsulfonyl chloride, please contact our sales team through the website or via direct inquiry, providing your specific requirements.

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