1-Undecanethiol
1-Undecanethiol (CAS 5332-52-5), with the chemical formula CH3(CH2)10SH and a molecular weight of 188.37 g/mol, is an alkyl thiol primarily utilised in materials science and micro/nanoelectronics. It is instrumental in forming self-assembled monolayers (SAMs) and serves as a spacer in mixed SAMs to create hydrophilic surfaces. Additionally, it functions effectively to minimise non-specific protein adsorption in various applications.
- IUPAC
- 1-UDT,11-Mercapto-1-undecanol,Undecyl Mercaptan
- Synonyms
- 1-UDTUndecyl Mercaptan11-Mercaptoundecanoic acidUndecane-1-thiol

Surface Modification
1-Undecanethiol is used to create well-ordered self-assembled monolayers (SAMs) on surfaces, particularly gold. These SAMs can be used to modify surface properties, such as wettability and adhesion.
Biomaterial Coatings
In biomaterials research, it is employed in mixed SAMs as spacers to provide a hydrophilic background, which helps in reducing non-specific protein adsorption and improving biocompatibility of surfaces.
Nanotechnology and Electronics
Its ability to form ordered monolayers makes it valuable in micro/nanoelectronics for fabricating precise structures and controlling surface interactions at the nanoscale.
Spacers in Mixed Monolayers
It functions as a spacer component in mixed SAM systems, allowing for the controlled presentation of other functional molecules or the creation of specific surface topographies.
| Molecular weight | 188.37 |
|---|---|
| Linear formula | CH3(CH2)10SH |
| Assay | 98% |
| Boiling point | 103-104 °C/3 mmHg(lit.) |
| Density | 0.841 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.459(lit.) |
| Application | Used to form hydrophilic SAMs and in mixed SAMs as spacers to provide a hydrophilic background. Also can be used to reduce non-specific protein adsorption. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 104 °C / 219.2 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Undecanethiol used for?
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1-Undecanethiol is used to form hydrophilic self-assembled monolayers (SAMs), act as spacers in mixed SAMs to provide a hydrophilic background, and to reduce non-specific protein adsorption. It finds applications in materials science and micro/nanoelectronics.
What are the CAS number and chemical formula for 1-Undecanethiol?
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The CAS number for 1-Undecanethiol is 5332-52-5 and its chemical formula is CH3(CH2)10SH.
What grade and purity does Tech Serve Solutions supply for 1-Undecanethiol?
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Tech Serve Solutions supplies 1-Undecanethiol with an assay of 98%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How is 1-Undecanethiol handled and what are the safety precautions?
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1-Undecanethiol is classified with GHS07 and a Warning signal word, carrying hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). It requires the use of eyeshields, gloves, and appropriate respiratory protection. Handle in a well-ventilated area.
How is 1-Undecanethiol packed, shipped, and exported?
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1-Undecanethiol is carefully packed according to international regulations for hazardous materials. Tech Serve Solutions has extensive experience in exporting chemicals globally, ensuring compliance with all necessary shipping and customs requirements.
How can I request a quote or sample of 1-Undecanethiol?
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To request a quote or a sample of 1-Undecanethiol, please visit the Tech Serve Solutions website or contact our sales team directly with your inquiry.
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