1-Thioglycerol
1-Thioglycerol (CAS: 96-27-5) is a sulfur-containing organic compound with the linear formula HSCH2CH(OH)CH2OH and a molecular weight of 108.16. This thiol, also known as 3-mercapto-1,2-propanediol, is a versatile building block used in chemical synthesis. Its unique structure featuring both thiol and diol functionalities makes it valuable for various organic transformations and material science applications.
- IUPAC
- α-Monothioglycerol,α-Thioglycerol,3-Mercapto-1,2-propanediol
- Synonyms
- 3-Mercapto-1,2-propanediolα-Monothioglycerolα-Thioglycerol
Chemical Synthesis Intermediate
1-Thioglycerol serves as a key intermediate in the synthesis of more complex organic molecules. Its thiol group can undergo various reactions like alkylation and addition, while the diol portion offers sites for esterification or etherification.
Reducing Agent
The thiol functionality allows 1-thioglycerol to act as a mild reducing agent in certain chemical processes. It can be employed to reduce disulfide bonds or participate in radical reactions.
Polymer Chemistry
Incorporated into polymer backbones or used as a modifying agent, 1-thioglycerol can impart specific properties to materials, such as increased hydrophilicity or sites for cross-linking.
| Molecular weight | 108.16 |
|---|---|
| Linear formula | HSCH2CH(OH)CH2OH |
| Assay | ≥98.0% (GC)~90% (RT) |
| Boiling point | 118 °C/5 mmHg(lit.) |
| Density | 1.25 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.527(lit.) |
| Storage temperature | 2-8°C |
| Impurities tested | ~10% water |
Hazard statements
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 21/22-36/37/38 |
| Safety statements (S) | 26-36 |
| Cation traces | Ca: ≤10 mg/kgCd: ≤1 mg/kgCo: ≤1 mg/kgCr: ≤1 mg/kgCu: ≤1 mg/kgFe: ≤1 mg/kgK: ≤20 mg/kgMg: ≤5 mg/kgMn: ≤1 mg/kgNa: ≤20 mg/kgNi: ≤1 mg/kgPb: ≤1 mg/kgZn: ≤1 mg/kg |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Thioglycerol used for?
+
1-Thioglycerol is primarily used as a building block in chemical synthesis, as a mild reducing agent, and in polymer chemistry.
What is the CAS number and formula for 1-Thioglycerol?
+
The CAS number for 1-Thioglycerol is 96-27-5, and its linear formula is HSCH2CH(OH)CH2OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-Thioglycerol with an assay of ≥98.0% (GC), containing approximately 10% water. We do not represent this product as USP, BP, or EP grade.
How should 1-Thioglycerol be handled safely?
+
1-Thioglycerol is classified as a Danger hazard. It is harmful if swallowed, toxic in contact with skin, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used.
How is 1-Thioglycerol packed, shipped, and exported?
+
1-Thioglycerol is packed and shipped according to relevant transportation regulations (UN 2810, Hazard Class 6.1). Tech Serve Solutions is a global supplier and exporter of fine chemicals.
How can I request a sample or quote for 1-Thioglycerol?
+
Please contact our sales department via the website or direct email to request a sample or a quotation for 1-Thioglycerol.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis