1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid
1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid (CAS 84358-12-3), with the molecular formula C11H19NO4 and a molecular weight of 229.27, is a versatile building block primarily utilised in chemical synthesis and peptide chemistry. This compound serves as an unnatural amino acid derivative, offering a protected form of nipecotic acid. Its structure makes it valuable for introducing specific piperidine moieties into complex molecules, aiding in the development of novel compounds within chemical biology and related research fields.
Peptide Synthesis
This compound is employed as a protected unnatural amino acid derivative in solid-phase or solution-phase peptide synthesis. It allows for the incorporation of a piperidine ring into peptide backbones, enabling the creation of peptidomimetics with modified conformational properties.
Chemical Synthesis Intermediate
As a valuable intermediate, it serves as a chiral building block for the synthesis of various organic molecules. The tert-butoxycarbonyl (Boc) protecting group can be readily removed under acidic conditions, revealing the free amine for further functionalization.
Drug Discovery and Medicinal Chemistry
The piperidine scaffold is prevalent in many pharmaceutical agents. This derivative provides a method to introduce this structural element during the early stages of drug discovery and the development of new therapeutic candidates.
Chemical Biology Research
Researchers in chemical biology utilise this compound to synthesise modified peptides or small molecules for probing biological pathways or developing chemical tools for biological studies.
| Molecular weight | 229.27 |
|---|---|
| Empirical formula | C11H19NO4 |
| Assay | 98% |
| Melting point | 159-162 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid used for?
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1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid is primarily used as a building block in chemical synthesis, particularly in peptide chemistry and for creating unnatural amino acid derivatives. It functions as an intermediate in the development of new organic molecules and pharmaceutical candidates.
What are the CAS number and molecular formula?
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The CAS number for 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid is 84358-12-3, and its empirical formula (Hill notation) is C11H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid with an assay of 98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
How should 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid be handled?
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This compound is classified as a skin, eye, and respiratory irritant (H315, H319, H335). When handling, use a dust mask type N95 (US), wear eyeshields and gloves, and ensure adequate ventilation. Avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do. Continue rinsing.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid. We can facilitate international shipments.
How can I request a sample or quote?
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To request a sample or a quote for 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid, please visit the product page on our website and use the relevant contact form or contact our sales team directly.
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