1-Nonyne
1-Nonyne (CAS: 3452-09-3), a terminal alkyne with the formula CH3(CH2)6C≡CH and a molecular weight of 124.22 g/mol, is a versatile organic building block. It is employed in chemical synthesis, particularly in the enantioselective construction of complex molecules. Its defined purity makes it suitable for advanced research and development applications requiring precise chemical transformations.

Enantioselective Synthesis
1-Nonyne serves as a key intermediate in the enantioselective synthesis of cladospolides. It has been specifically utilised in the synthesis of cladospolide B, C, and (ent)-cladospolide D, demonstrating its utility in creating stereochemically defined natural products.
Organic Synthesis Building Block
As a terminal alkyne, 1-Nonyne is a valuable reagent in various organic transformations. It can participate in addition reactions, coupling reactions, and cycloadditions, enabling the construction of more complex carbon frameworks.
Research and Development
This compound is utilised in academic and industrial research settings for exploring new synthetic methodologies and developing novel organic compounds. Its availability as a high-purity chemical facilitates reproducible experimental outcomes.
| Molecular weight | 124.22 |
|---|---|
| Linear formula | CH3(CH2)6C≡CH |
| Assay | 99% |
| Boiling point | 150-151 °C(lit.) |
| Density | 0.757 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.422(lit.) |
| Vapour pressure | 16 mmHg (37.7 °C) |
| Melting point | −50 °C(lit.) |
| Application | 1-Nonyne has been used in enantioselective synthesis of cladospolide B, C and (ent)-cladospolide D1. |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 34 °C / 93.2 °F |
| Transport (UN / ADR) | UN 3295C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Nonyne used for?
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1-Nonyne is used as a building block in organic synthesis and has been employed in the enantioselective synthesis of cladospolides.
What is the CAS number and formula for 1-Nonyne?
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The CAS number for 1-Nonyne is 3452-09-3, and its linear formula is CH3(CH2)6C≡CH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Nonyne with a minimum assay of 99%. This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 1-Nonyne be handled safely?
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1-Nonyne is a flammable liquid and vapour (H226), and causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and ensure adequate ventilation in a well-equipped laboratory.
Is 1-Nonyne a controlled substance?
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The provided data does not indicate that 1-Nonyne is a controlled substance.
How is 1-Nonyne packed and exported?
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1-Nonyne is shipped according to UN 3295C 3 / PGIII regulations. As a specialist global supplier, Tech Serve Solutions exports fine chemicals worldwide.
How can I request a sample or quote for 1-Nonyne?
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Please contact our sales department via the website to request a sample or a quotation for 1-Nonyne.
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