1-Naphthyl butyrate
1-Naphthyl butyrate (CAS: 3121-70-8), with the molecular formula C14H14O2 and a molecular weight of 214.26 g/mol, is a chemical compound utilised as an esterase substrate. It functions as a chromogenic reagent, particularly valuable in biochemical and enzymatic assays. Its application is primarily in research and diagnostic settings for detecting esterase activity, contributing to a better understanding of biological processes and disease mechanisms.
- IUPAC
- Butanoic acid 1-naphthyl ester,Butyric acid 1-naphthyl ester
- Synonyms
- Butanoic acid 1-naphthyl esterButyric acid 1-naphthyl ester

Esterase Activity Detection
1-Naphthyl butyrate serves as a specific substrate for esterase enzymes. Upon enzymatic hydrolysis, it releases 1-naphthol, which can then be quantified or visualised, enabling the detection and measurement of esterase activity in various biological samples.
Biochemical Research
In biochemical research, this compound is employed to study enzyme kinetics, identify esterase isoforms, and investigate their physiological roles. Its use aids in the characterisation of enzymes involved in metabolic pathways and cellular signalling.
Chromogenic Reagent
As a chromogenic reagent, 1-Naphthyl butyrate facilitates qualitative and quantitative analysis. The resulting colour change after enzymatic action provides a visual or measurable output, making it a useful tool in diagnostic kits and laboratory testing.
| Molecular weight | 214.26 |
|---|---|
| Linear formula | CH3CH2CH2CO2C10H7 |
| Boiling point | 125-130 °C/1 mmHg(lit.) |
| Density | 1.091 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.571(lit.) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 62 °C / 143.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | esterase substrate |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Naphthyl butyrate used for?
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1-Naphthyl butyrate is primarily used as an esterase substrate and a chromogenic reagent in biochemical assays to detect and measure esterase activity.
What is the CAS number and molecular formula for 1-Naphthyl butyrate?
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The CAS number is 3121-70-8, and the molecular formula is C14H14O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Naphthyl butyrate for research and technical applications. The specific purity or assay is available on the product's Certificate of Analysis; we do not represent this product as USP, BP, or EP grade.
How should 1-Naphthyl butyrate be handled and stored?
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Handle 1-Naphthyl butyrate with appropriate personal protective equipment, including eyeshields and gloves. Store at -20°C as indicated. Refer to the Safety Data Sheet for comprehensive handling and hazard information, noting the flash point of 62°C.
Is 1-Naphthyl butyrate shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-Naphthyl butyrate, compliant with international shipping regulations such as NA 1993.
How can I request a quote or sample?
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To request a quote or a sample of 1-Naphthyl butyrate, please contact our sales department through the website or via the provided contact details.
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