1-Naphthyl acetate
1-Naphthyl acetate (CAS: 830-81-9, Formula: C12H10O2, MW: 186.21) is a key organic compound used extensively as an enzyme substrate. It is particularly valuable in biochemical research for the identification and characterization of esterase activity, notably in the rapid staining method for macrophages. Supplied by Tech Serve Solutions, this chemical meets high standards for research and diagnostic applications.
- IUPAC
- α-Naphthyl acetate
- Synonyms
- α-Naphthyl acetate
Esterase Activity Detection
1-Naphthyl acetate serves as a crucial chromogenic substrate for detecting esterase activity. Its hydrolysis by esterases produces naphthol, which can then be coupled to form a coloured precipitate, enabling visualisation of enzyme location and activity in biological samples.
Macrophage Identification
This compound is employed in a rapid staining method for the identification of macrophages. The method's accuracy has been validated against morphological criteria, phagocytosis, and Fc receptor presence, making it a reliable tool in immunological studies.
Biochemical Research Reagent
As a versatile reagent, 1-Naphthyl acetate is utilized in various biochemical and enzymatic assays. Its defined reactivity makes it suitable for research laboratories investigating enzyme kinetics and substrate specificity.
| Molecular weight | 186.21 |
|---|---|
| Linear formula | CH3CO2C10H7 |
| Assay | ≥99.0% (HPLC) |
| Solubility | dioxane: soluble0.1 g/mL, clear, colorless |
| Impurities tested | ≤0.1% free naphthol |
| Application | Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors.1 |
| Melting point | 43-46 °C(lit.)45-46 °C |
Hazard statements
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Naphthyl acetate used for?
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1-Naphthyl acetate is primarily used as an enzyme substrate, particularly for detecting esterase activity and in rapid staining methods for identifying macrophages in biological research.
What are the CAS number and formula for 1-Naphthyl acetate?
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The CAS number for 1-Naphthyl acetate is 830-81-9, and its linear formula is CH3CO2C10H7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Naphthyl acetate with an assay of ≥99.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 1-Naphthyl acetate be handled safely?
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1-Naphthyl acetate causes serious eye damage (H318). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid contact with eyes and ensure good ventilation.
Is 1-Naphthyl acetate a controlled substance?
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The provided data does not indicate that 1-Naphthyl acetate is a controlled substance.
How is 1-Naphthyl acetate packed and exported by TSS?
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Tech Serve Solutions, a global supplier and exporter, ensures appropriate packing for chemical integrity and compliance with international shipping regulations for all its products, including 1-Naphthyl acetate.
How can I request a quote or sample for 1-Naphthyl acetate?
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Please contact the Tech Serve Solutions sales team via our website or direct inquiry channels to request a quote or sample for 1-Naphthyl acetate.
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