1-Iodo-2-(trimethylsilyl)acetylene
1-Iodo-2-(trimethylsilyl)acetylene (CAS: 18163-47-8) is a halogenated hydrocarbon and an organic building block with a molecular weight of 224.11 g/mol. This alkynyl compound serves as a valuable intermediate in organic synthesis, particularly for introducing the trimethylsilyl-protected acetylene moiety into complex molecules. Its reactivity makes it useful in cross-coupling reactions and as a precursor for novel materials and pharmaceuticals.
Organic Synthesis Intermediate
Utilised as a versatile building block in the construction of complex organic molecules. Its trimethylsilyl group acts as a protecting group for the alkyne, allowing for selective functionalization.
Cross-Coupling Reactions
Serves as a coupling partner in reactions such as Sonogashira coupling, enabling the formation of carbon-carbon bonds and the synthesis of conjugated systems.
Material Science Precursor
Can be employed in the synthesis of novel polymers and advanced materials due to its unique alkynyl and silyl functionalities.
| Molecular weight | 224.11 |
|---|---|
| Linear formula | (CH3)3SiC≡CI |
| Assay | 97% |
| Boiling point | 130 °C(lit.) |
| Density | 1.46 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.511(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H317May cause an allergic skin reaction
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 48 °C / 118.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-10-20/21/22-42/43 |
| Safety statements (S) | 16-23-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Iodo-2-(trimethylsilyl)acetylene used for?
+
1-Iodo-2-(trimethylsilyl)acetylene is primarily used as an intermediate in organic synthesis, particularly in cross-coupling reactions and for the preparation of advanced materials and complex organic molecules.
What is the CAS number and formula for 1-Iodo-2-(trimethylsilyl)acetylene?
+
The CAS number for 1-Iodo-2-(trimethylsilyl)acetylene is 18163-47-8. Its linear formula is (CH₃)₃SiC≡CI.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-Iodo-2-(trimethylsilyl)acetylene with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How is 1-Iodo-2-(trimethylsilyl)acetylene handled and stored?
+
This compound is flammable (flash point 48 °C) and harmful if swallowed, inhaled, or in contact with skin. It may cause an allergic skin reaction and potential genetic defects. Store at 2-8°C in a well-ventilated place, away from ignition sources.
How are TSS products packed, shipped, and exported?
+
Tech Serve Solutions professionally packs and ships chemicals globally, adhering to all relevant transportation regulations for hazardous materials like UN 1993 C 3 / PGIII.
How can I request a quote or sample?
+
To request a quote or sample, please contact our sales department through the website or call us directly. Our team will assist you promptly.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
