1-Iodo-1-hexyne
1-Iodo-1-hexyne (CAS: 1119-67-1; Formula: IC₂H₅(CH₂)₃CH₃; MW: 208.04) is a halogenated alkyne. This terminal iodoalkyne serves as a valuable building block in organic synthesis. It is particularly useful for introducing the hexynyl group into various molecular structures through reactions such as Sonogashira coupling and other cross-coupling methodologies. Its utility spans research and development in pharmaceuticals and materials science.
Organic Synthesis Intermediate
1-Iodo-1-hexyne is frequently employed as a key intermediate in the synthesis of complex organic molecules. Its terminal alkyne functionality allows for facile derivatization via click chemistry and various metal-catalyzed cross-coupling reactions.
Pharmaceutical Research
This compound is used in the development of novel pharmaceutical agents. It enables the construction of alkynyl-containing pharmacophores, which can modulate biological activity and pharmacokinetic properties of drug candidates.
Materials Science
The incorporation of alkynyl units via 1-Iodo-1-hexyne can be used to create functionalised polymers and advanced materials. These materials may exhibit unique electronic or optical properties relevant to optoelectronics and advanced coatings.
| Molecular weight | 208.04 |
|---|---|
| Linear formula | IC2(CH2)3CH3 |
| Assay | ≥97.0% (GC) |
| Density | 1.564 at 20 °C |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 67 °C / 152.6 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Iodo-1-hexyne used for?
+
1-Iodo-1-hexyne is primarily used as a building block in organic synthesis for creating complex molecules, particularly in pharmaceutical research and materials science. It is valuable for reactions like Sonogashira coupling.
What is the CAS number and formula for 1-Iodo-1-hexyne?
+
The CAS number for 1-Iodo-1-hexyne is 1119-67-1, and its linear formula is IC₂H₅(CH₂)₃CH₃.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 1-Iodo-1-hexyne with an assay of ≥97.0% (GC). This is a research grade chemical; TSS does not represent it as USP, BP, EP, or other pharmacopoeial standards.
What are the safety hazards associated with 1-Iodo-1-hexyne?
+
1-Iodo-1-hexyne is classified as a Warning substance. It causes skin irritation (H315) and serious eye irritation (H319). Appropriate personal protective equipment, including gloves, eye protection, and protective clothing, should be worn when handling.
How is 1-Iodo-1-hexyne packaged and shipped?
+
1-Iodo-1-hexyne is typically packaged according to industry standards for fine chemicals and is shipped as a non-hazardous material (NA 1993, PGIII) suitable for international export. It requires storage at 2-8°C.
How can I request a quote or sample for 1-Iodo-1-hexyne?
+
To request a quote or a sample of 1-Iodo-1-hexyne, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis