1-Fluoro-2,4,6-trimethylpyridinium triflate
1-Fluoro-2,4,6-trimethylpyridinium triflate (CAS 107264-00-6) is a key fluorinating and oxidising reagent with a molecular weight of 289.25 g/mol. It is extensively employed in organic synthesis, particularly in C-H activation, fluorination reactions, and oxidative bond formations. This compound serves as a valuable tool for chemists seeking efficient methods for introducing fluorine atoms or facilitating palladium-catalyzed transformations. Tech Serve Solutions supplies this reagent at 95% purity.
- IUPAC
- 1-Fluoro-sym-collidinium triflate
- Synonyms
- 107264-00-6C9H11F4NO3S1-Fluoro-sym-collidinium triflate

C-H Activation Reactions
This pyridinium salt is a valuable reactant in palladium(II)-catalyzed para-selective C-H arylation, enabling the direct functionalisation of aromatic C-H bonds.
Fluorination Chemistry
It serves as an effective reagent in various fluorination reactions, facilitating the introduction of fluorine atoms into organic molecules.
Oxidative Aryl-CF3 Bond Formation
The compound acts as an oxidant in reactions that promote the formation of aryl-CF3 bonds through oxidative processes.
C-H Olefination
It is utilised in palladium(II)-catalyzed C-H olefination reactions, contributing to the synthesis of complex organic structures.
| Molecular weight | 289.25 |
|---|---|
| Empirical formula | C9H11F4NO3S |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Application | Reactant for:• Pd(II)-catalyzed para-selective C-H arylation1• Fluorination reactions2• Oxidant in oxidatively-induced aryl-CF3 bond-formation3• Pd(II)-catalyzed C-H olefination reactions4 |
| Melting point | 162-165 °C(lit.)164-170 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Transport (UN / ADR) | UN 3261 8 / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Fluoro-2,4,6-trimethylpyridinium triflate used for?
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1-Fluoro-2,4,6-trimethylpyridinium triflate is primarily used as a reagent in C-H activation, fluorination reactions, and oxidative bond-formation processes, including Pd(II)-catalyzed C-H arylation and olefination.
What are the CAS number and formula for this compound?
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The CAS number is 107264-00-6, and its empirical formula in Hill notation is C9H11F4NO3S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Fluoro-2,4,6-trimethylpyridinium triflate with an assay of 95%. This product is not represented as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
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This compound is classified as dangerous and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including gloves, eye protection, and protective clothing. Ensure adequate ventilation. In case of contact, rinse immediately with plenty of water and seek medical advice. Store at 2-8°C.
How is 1-Fluoro-2,4,6-trimethylpyridinium triflate packed and exported?
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This chemical is packed and shipped according to international regulations for hazardous materials, including UN 3261, Class 8, PGII. We export globally.
How can I request a quote or sample?
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To request a quote or a sample, please use the contact form on our website or call our sales department, providing the product name and CAS number (107264-00-6).
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