1-Ethynylcyclohexylamine
1-Ethynylcyclohexylamine (CAS: 30389-18-5), with the chemical formula HC≡CC<sub>6</sub>H<sub>10</sub>NH<sub>2</sub> and a molecular weight of 123.20 g/mol, is a valuable organic building block. This terminal alkyne features a cyclohexyl ring and an amine group, making it suitable for diverse synthetic applications. It is primarily utilised in chemical synthesis for the construction of complex molecular architectures, including bicyclic and tetracyclic compounds.
Synthesis of Bicyclic and Tetracyclic Compounds
1-Ethynylcyclohexylamine has been employed as a key intermediate in the synthesis of complex organic molecules. Its structure facilitates the formation of fused ring systems, contributing to the development of novel chemical entities.
Substrate in Mercury(II)-Catalysed Reactions
The compound serves as a substrate in reactions involving alkynes and mercury(II) acetate. This application highlights its utility in organometallic chemistry and specific catalytic transformations.
Organic Building Block
As an organic building block, 1-Ethynylcyclohexylamine offers a unique combination of a terminal alkyne and a primary amine on a cyclohexyl scaffold. This makes it a versatile reagent for introducing specific functionalities in organic synthesis.
| Molecular weight | 123.20 |
|---|---|
| Linear formula | HC≡CC6H10NH2 |
| Assay | 98% |
| Boiling point | 65-66 °C/20 mmHg(lit.) |
| Density | 0.913 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.482(lit.) |
| Application | 1-Ethynylcyclohexylamine was used in the synthesis of bicyclic and tetracyclic compounds1. It was also used as a substrate in the reaction of a series of alkynes with mercury(II)acetate2. |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 42 °C / 107.6 °F |
| Transport (UN / ADR) | UN 2734 8/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Ethynylcyclohexylamine used for?
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1-Ethynylcyclohexylamine is used in chemical synthesis, notably for the preparation of bicyclic and tetracyclic compounds and as a substrate in reactions with mercury(II) acetate.
What are the CAS number and formula for 1-Ethynylcyclohexylamine?
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The CAS number is 30389-18-5, and the chemical formula is HC≡CC<sub>6</sub>H<sub>10</sub>NH<sub>2</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Ethynylcyclohexylamine with an assay of 98%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 1-Ethynylcyclohexylamine be handled safely?
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1-Ethynylcyclohexylamine is a flammable liquid and causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Store away from ignition sources.
Is 1-Ethynylcyclohexylamine shipped internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of chemicals, including 1-Ethynylcyclohexylamine.
How can I request a quote or sample for 1-Ethynylcyclohexylamine?
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Please contact our sales team through our website or by phone to request a quote or sample for 1-Ethynylcyclohexylamine.
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