1-EBIO

CAS 10045-45-1C9H10N2OCell Biology

1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one (CAS: 10045-45-1), with the molecular formula C9H10N2O and a molecular weight of 162.19 g/mol, is a chemical compound primarily utilised in biological research. It serves as a valuable tool for investigating the electrical activity of neurons and the function of ion channels, particularly potassium channels, in various biological systems. Its applications extend to studying cell signalling pathways and neuronal function.

IUPAC: 1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one; 1-Ethylbenzimidazolinone
Synonyms: 1-Ethylbenzimidazolinone

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1-EBIO (C9H10N2O) — chemical structure, CAS 10045-45-1; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyIon ChannelsMonovalent Ion ChannelsPotassium Channel Modulators

01 /Applications

Investigation of Calcium-Activated Potassium Channels

1-EBIO has been employed in research to examine the electrical activity modulated by Ca+2-activated K+ channels in central neurons of rats, providing insights into neuronal excitability. This compound aids in understanding the role of these channels in neural function.

Study of Intermediate Conductance Potassium Channels

The effects of 1-EBIO on human intermediate conductance channels have been a subject of study. This research contributes to a deeper understanding of the structure and function of these crucial ion channels in cellular processes.

Cellular Electrophysiology Research

As a modulator of ion channel activity, 1-EBIO is a useful reagent in electrophysiology studies. It helps researchers probe the mechanisms underlying membrane potential and cellular communication.

02 /Properties

Molecular weight	162.19
Empirical formula	C9H10N2O
Assay	≥98% (HPLC)
Form	powder
Solubility	DMSO: ≥20 mg/mL
Storage temperature	room temp
Application	1-EBIO was used to study the electrical activity modulated by Ca+2-activated K+ channels in rat central neurons.1 The effect of 1-EBIO on human intermediate conductance channels was studied.2

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-36
Safety statements (S)	26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

10045-45-1

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 1-EBIO used for?

1-EBIO is used in research to study the electrical activity modulated by Ca+2-activated K+ channels in rat central neurons and to investigate the effects on human intermediate conductance channels. It is also used in broader cell signalling and neuroscience research, particularly concerning ion channels.

What are the CAS number and formula for 1-EBIO?

The CAS number for 1-EBIO is 10045-45-1, and its empirical formula is C9H10N2O.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 1-EBIO with a purity of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should 1-EBIO be handled safely?

1-EBIO is harmful if swallowed and causes serious eye irritation (H302, H319). Handle with appropriate personal protective equipment, including gloves and eye protection. In case of eye contact, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Seek medical advice if swallowed. Store at room temperature.

Is 1-EBIO available for international export?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 1-EBIO, and can fulfil international orders.

How can I request a sample or quote for 1-EBIO?

To request a sample or obtain a quote for 1-EBIO, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.