1-Azakenpaullone
1-Azakenpaullone (CAS 676596-65-9), with the molecular formula C15H10BrN3O and a molecular weight of 328.16 g/mol, is a gray-brown powder. This compound is primarily utilised in biochemical research, particularly within cell biology and kinase/phosphatase signalling pathways. Its role as an inhibitor of serine/threonine kinases, including GSK3, makes it a valuable tool for studying cellular processes and potential therapeutic targets.
- IUPAC
- 9-Bromo-7,12-dihydro-pyrido[3′,2′:2,3]azepino[4,5-b]indol-6(5H)-one
GSK3 Inhibition Studies
1-Azakenpaullone serves as a potent inhibitor of Glycogen Synthase Kinase 3 (GSK3). Researchers use this compound to investigate the roles of GSK3 in various cellular functions, including metabolism, cell survival, and neurodevelopment.
Cell Signaling Research
As a tool in cell signaling research, 1-Azakenpaullone helps elucidate the downstream effects of GSK3 inhibition. It aids in understanding complex signaling cascades relevant to cell biology and neuroscience.
Serine/Threonine Kinase Biology
This compound is instrumental in studying serine/threonine kinase biology, providing a specific means to modulate kinase activity. Its use allows for detailed investigation into the function and regulation of these critical enzymes.
| Molecular weight | 328.16 |
|---|---|
| Empirical formula | C15H10BrN3O |
| Assay | ≥97% (HPLC) |
| Form | powder |
| Colour | gray-brown |
| Solubility | DMSO: >10 mg/mL |
| Storage temperature | 2-8°C |
| Storage Condition | protect from light |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Azakenpaullone used for?
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1-Azakenpaullone is used in biochemical research, primarily for studying cell biology, cell signaling, and as an inhibitor of Glycogen Synthase Kinase 3 (GSK3) and other serine/threonine kinases.
What are the CAS number and formula for 1-Azakenpaullone?
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The CAS number for 1-Azakenpaullone is 676596-65-9, and its empirical formula is C15H10BrN3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Azakenpaullone with an assay of ≥97% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling considerations for 1-Azakenpaullone?
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According to the provided data, 1-Azakenpaullone has a WGK Germany rating of 2, indicating it is hazardous to water. It should be handled with appropriate personal protective equipment in a well-ventilated area. Consult the Safety Data Sheet (SDS) for comprehensive safety information.
How is 1-Azakenpaullone shipped and exported?
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Tech Serve Solutions, as a global supplier and exporter since 1998, can ship and export 1-Azakenpaullone worldwide, adhering to all necessary regulations for chemical transport.
How can I request a quote or sample for 1-Azakenpaullone?
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To request a quote or a sample of 1-Azakenpaullone, please contact our sales department through the website or by telephone.
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