1-Bromo-4-fluorobutane
1-Bromo-4-fluorobutane (CAS: 462-72-6) is a halogenated hydrocarbon with the chemical formula F(CH2)4Br and a molecular weight of 155.01 g/mol. This clear liquid serves as a valuable building block in organic synthesis. Its unique difunctional structure, featuring both a bromine and a fluorine atom, allows for diverse chemical transformations, making it a key intermediate in the development of complex molecules for various research and industrial applications. Supplied with 98% purity.

Organic Synthesis Intermediate
1-Bromo-4-fluorobutane is utilised as a versatile alkylating agent in organic chemistry. It is instrumental in introducing a 4-fluorobutyl chain into various molecular structures, facilitating the synthesis of more complex compounds.
Pharmaceutical Research
This compound serves as a precursor in the synthesis of novel pharmaceutical agents. The presence of fluorine can modulate the pharmacokinetic properties of drug candidates, making it an attractive building block in medicinal chemistry.
Material Science
The incorporation of fluorinated moieties can impart specific properties to materials. 1-Bromo-4-fluorobutane can be employed in the development of specialised polymers or functional materials where its structural features are beneficial.
Agrochemical Development
It may be used in the synthesis pathways for new agrochemicals, contributing to the development of compounds with desired biological activity and environmental profiles.
| Molecular weight | 155.01 |
|---|---|
| Linear formula | F(CH2)4Br |
| Assay | 98% |
| Boiling point | 134-135 °C(lit.) |
| Density | 1.444 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.439(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 45 °C / 113 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-4-fluorobutane used for?
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1-Bromo-4-fluorobutane is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and the development of specialised materials and agrochemicals.
What are the CAS number and chemical formula for 1-Bromo-4-fluorobutane?
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The CAS number for 1-Bromo-4-fluorobutane is 462-72-6, and its chemical formula is F(CH2)4Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Bromo-4-fluorobutane with a purity of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated.
What are the main safety hazards associated with 1-Bromo-4-fluorobutane?
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1-Bromo-4-fluorobutane is a flammable liquid and vapour (H226). It is harmful if swallowed (H302), in contact with skin (H312), or if inhaled (H332). It also causes skin irritation (H315) and serious eye irritation (H319). Inhalation may cause respiratory irritation (H335).
How is 1-Bromo-4-fluorobutane packed and exported?
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1-Bromo-4-fluorobutane is carefully packed according to international shipping regulations for hazardous materials, including UN 1993 classification, and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for 1-Bromo-4-fluorobutane?
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To request a quote or a sample, please contact our sales team through the website or direct inquiry channels, providing your details and the product name and CAS number.
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