1-Boc-3-(aminomethyl)pyrrolidine
1-Boc-3-(aminomethyl)pyrrolidine (CAS: 270912-72-6; Formula: C10H20N2O2; Mol. Wt.: 200.28) is a protected pyrrolidine derivative. It serves as a valuable building block in organic synthesis, particularly within pharmaceutical research and development. Its structure allows for further functionalization, making it a versatile intermediate for creating complex molecules. The Boc protecting group offers stability during synthetic transformations and can be readily removed when required.
- IUPAC
- tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate
- Synonyms
- tert-Butyl 3-(aminomethyl)pyrrolidine-1-carboxylate

Pharmaceutical Intermediate
Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its pyrrolidine core is a common motif in many biologically active compounds.
Organic Synthesis Building Block
A versatile reagent for constructing complex organic molecules. The primary amine and the Boc-protected secondary amine allow for selective derivatization.
Peptide and Peptidomimetic Research
Incorporated into peptidomimetics or modified peptides to enhance stability or alter biological activity. The pyrrolidine ring can act as a proline surrogate.
Chemical Research
Employed in academic and industrial research labs for exploring novel chemical reactions and developing new synthetic methodologies.
| Molecular weight | 200.28 |
|---|---|
| Empirical formula | C10H20N2O2 |
| Storage temperature | 2-8°C |
| Melting point | 206-210 °C |


Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P305IF IN EYES
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 22-36-50 |
| Safety statements (S) | 26-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-3-(aminomethyl)pyrrolidine used for?
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1-Boc-3-(aminomethyl)pyrrolidine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical intermediates and research chemicals.
What is the CAS number and formula for 1-Boc-3-(aminomethyl)pyrrolidine?
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The CAS number is 270912-72-6 and the empirical formula is C10H20N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Boc-3-(aminomethyl)pyrrolidine as a research or technical grade chemical. We do not represent it as USP, BP, EP, or pharmacopoeia grade unless explicitly stated otherwise in the product specifications.
How should 1-Boc-3-(aminomethyl)pyrrolidine be handled safely?
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1-Boc-3-(aminomethyl)pyrrolidine is classified with GHS07 and GHS09 symbols, bearing the signal word 'Warning'. It carries hazard statements H302 (Harmful if swallowed), H319 (Causes serious eye irritation), and H400 (Very toxic to aquatic life). Handle with appropriate personal protective equipment in a well-ventilated area, avoiding release to the environment. Refer to the Safety Data Sheet for full details.
How is 1-Boc-3-(aminomethyl)pyrrolidine packed, shipped, and exported?
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This product is packed according to industry standards for chemical reagents and is exported globally by Tech Serve Solutions. Shipping complies with relevant regulations for hazardous materials, including UN 3077 classification.
How can I request a sample or quote for 1-Boc-3-(aminomethyl)pyrrolidine?
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To request a sample or a quote, please contact our sales team through the website or by calling our customer service line. Please provide your specific requirements and shipping details.
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