1-Benzylindole-3-carboxaldehyde
1-Benzylindole-3-carboxaldehyde (CAS: 10511-51-0) is a key organic intermediate with the molecular formula C16H13NO and a molecular weight of 235.28 g/mol. This indole derivative functions as a versatile building block in organic synthesis. It is primarily utilised as a reactant in the preparation of various biologically active compounds, including inhibitors for RNA polymerase II and Bcl-2 family proteins, and in Nazarov-type electrocyclization reactions. It is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- 1-Benzyl-3-formylindole,NSC 95434
- Synonyms
- 1-Benzyl-3-formylindole, NSC 95434
Inhibitor Synthesis
Utilised as a reactant in the synthesis of inhibitors targeting the C-terminal domain of RNA polymerase II and Bcl-2 family proteins, crucial for biological research.
Nazarov Electrocyclization
Serves as a reactant in Nazarov type electrocyclization reactions, a significant transformation in organic chemistry for forming cyclic compounds.
Mannich-type Coupling
Employed as a reactant for Mannich type coupling reactions with aldehydes and secondary amines, facilitating the formation of complex molecular structures.
| Molecular weight | 235.28 |
|---|---|
| Empirical formula | C16H13NO |
| Storage temperature | −20°C |
| Application | • reactant in preparation of inhibitor of the C-terminal domain of RNA polymerase II1• reactant in Nazarov type electrocyclization2• reactant in preparation inhibitors of Bcl-2 family of proteins3• reactant for Mannich type coupling with aldehydes and secondary amines4 |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Benzylindole-3-carboxaldehyde used for?
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1-Benzylindole-3-carboxaldehyde is used as a reactant in organic synthesis, notably in the preparation of inhibitors for RNA polymerase II and Bcl-2 family proteins, and in Nazarov type electrocyclization reactions.
What are the CAS number and formula for 1-Benzylindole-3-carboxaldehyde?
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The CAS number is 10511-51-0 and the empirical formula is C16H13NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Benzylindole-3-carboxaldehyde as a research-grade chemical. The specific assay is available on the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling 1-Benzylindole-3-carboxaldehyde?
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1-Benzylindole-3-carboxaldehyde is classified as a Warning substance. It is harmful if swallowed (H302) and may cause an allergic skin reaction (H317). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, face shields, and gloves, should be worn. Handle in a well-ventilated area.
Is 1-Benzylindole-3-carboxaldehyde available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1-Benzylindole-3-carboxaldehyde, and can fulfil international orders.
How can I request a sample or quote for 1-Benzylindole-3-carboxaldehyde?
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To request a sample or a quotation, please contact our sales department through the details provided on the Tech Serve Solutions website.
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