1-Benzoyl-4-piperidone
1-Benzoyl-4-piperidone (CAS: 24686-78-0, C12H13NO2) is a key chemical intermediate with a molecular weight of 203.24 g/mol. This compound serves as a crucial building block in organic synthesis, particularly noted for its utility in the preparation of more complex molecular structures. Its well-defined chemical properties make it a valuable reagent for research and development purposes within the chemical industry.

Synthesis of Fentanyl Analogues
1-Benzoyl-4-piperidone is a documented starting reagent in the synthesis of fentanyl and its analogues. Its structure provides a core scaffold for the elaboration of potent opioid analgesics. Strict regulatory controls are associated with its handling and use due to this application.
Organic Synthesis Intermediate
As a versatile heterocyclic building block, this piperidone derivative can be employed in a variety of organic transformations. It offers a functionalised piperidine ring suitable for further chemical modification in the development of novel compounds.
Research and Development
This compound is utilised in chemical research laboratories for exploring new synthetic pathways and developing novel chemical entities. Its availability facilitates academic and industrial R&D projects.
| Molecular weight | 203.24 |
|---|---|
| Empirical formula | C12H13NO2 |
| Assay | 97% |
| Boiling point | 158-160 °C/0.2 mmHg(lit.) |
| Solubility | methylene chloride: soluble |
| Application | 1-Benzoyl-4-piperidone can be used as starting reagent in the synthesis of fentanyl. |
| Melting point | 55-59 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Benzoyl-4-piperidone used for?
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1-Benzoyl-4-piperidone (CAS: 24686-78-0) is primarily used as a starting reagent in the synthesis of fentanyl and its analogues, and as a general intermediate in organic synthesis and chemical research.
What is the CAS number and chemical formula for 1-Benzoyl-4-piperidone?
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The CAS number is 24686-78-0, and the chemical formula is C12H13NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Benzoyl-4-piperidone with a minimum assay of 97%. This product is typically considered a technical or research grade material and is not represented as USP, BP, EP, or any pharmacopoeia standard.
How should 1-Benzoyl-4-piperidone be handled safely?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter such as type N95 (US) or P1 (EN143) is recommended. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions and hazard information. It has a flash point of 113 °C.
Is 1-Benzoyl-4-piperidone a controlled substance?
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Yes, due to its use in the synthesis of fentanyl, 1-Benzoyl-4-piperidone is a listed precursor chemical and is subject to strict regulatory controls in many jurisdictions. Customers must comply with all applicable laws and regulations.
How is 1-Benzoyl-4-piperidone packed and shipped?
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Tech Serve Solutions packs and ships chemicals according to international safety standards and regulations. Specific packaging details depend on quantity and destination, ensuring secure and compliant transport for export.
How can I request a sample or quote for 1-Benzoyl-4-piperidone?
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To request a sample or obtain a quotation for 1-Benzoyl-4-piperidone, please contact our sales department via the website or direct email, providing your contact details and intended use.
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