1-Amino-1-cyclobutanecarboxylic acid
1-Amino-1-cyclobutanecarboxylic acid (CAS: 22264-50-2), with the molecular formula C4H9NO2 and a molecular weight of 115.13 g/mol, is an alicyclic amino acid. This compound serves as a valuable building block in chemical synthesis, particularly within the fields of chemical biology and peptide chemistry. It is recognised for its role in the development of unnatural amino acid derivatives, contributing to novel molecular structures and research applications.

Chemical Synthesis Intermediate
Utilised as a key intermediate in organic synthesis, offering a cyclobutane ring structure functionalised with both amine and carboxylic acid groups. Its unique structure facilitates the construction of complex molecules.
Peptide Chemistry Research
Incorporated into peptide chains to create unnatural amino acid derivatives. This aids in the study of peptide structure-activity relationships and the development of novel peptidomimetics.
Chemical Biology Studies
Applied in chemical biology research to explore novel biochemical pathways and molecular interactions. It can be used to synthesise probes or modified biomolecules for investigative purposes.
| Molecular weight | 115.13 |
|---|---|
| Linear formula | H2NC4H6CO2H |
| Assay | 97% |
| Melting point | 261 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Amino-1-cyclobutanecarboxylic acid used for?
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1-Amino-1-cyclobutanecarboxylic acid is primarily used as an intermediate in chemical synthesis, particularly for creating unnatural amino acid derivatives relevant to peptide chemistry and chemical biology research.
What are the CAS number and molecular formula for 1-Amino-1-cyclobutanecarboxylic acid?
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The CAS number is 22264-50-2, and the molecular formula is C4H9NO2 (or H2NC4H6CO2H).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Amino-1-cyclobutanecarboxylic acid with a purity of 97%. This product is suitable for research and general chemical synthesis purposes. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 1-Amino-1-cyclobutanecarboxylic acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, faceshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified as harmful if swallowed and causes skin, eye, and respiratory irritation.
Is 1-Amino-1-cyclobutanecarboxylic acid exported by TSS?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 1-Amino-1-cyclobutanecarboxylic acid, to laboratories and industries worldwide.
How can I request a sample or quote for 1-Amino-1-cyclobutanecarboxylic acid?
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To request a sample or a quote, please contact our sales department via the website or email, providing your contact details and the quantity required.
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